Publications by authors named "Lenin Nayagam"

Article Synopsis
  • A solvent casting technique was employed to create biomimetic nanocomposite scaffolds using varying concentrations of Curcumin-loaded gold nanoparticles (Cur-AuNPs) combined with chitosan-sodium alginate.
  • The physicochemical properties of the Cur-AuNPs and the resulting nanocomposites were analyzed through various characterization methods, focusing on their biocompatibility and antibacterial activity.
  • These studies indicate that Cur-AuNPs integrated with biomimetic nanocomposites have potential applications for nanotheranostics in targeted therapies.
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Facile one-pot synthesis has been demonstrated for new biocompatible and dual responsive magnetic iron oxide nanoparticles cross-linked poly(vinyl alcohol) (PVA) blended natural polymer chitosan (CS) based hydrogel beads (mCS-PVA) as a controlled natural anticancer alkaloid Luotonin A (LuA) delivery system. The prepared magnetic hydrogel beads were characterized using powder X-ray diffraction measurement, Fourier transform-infrared spectroscopy, scanning electron microscopy, energy dispersive X-ray spectroscopy, and vibrating sample magnetometer. The magnetic hydrogel beads are exhibited significant water retention and follow the second order kinetic model in swelling study.

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