Corticomedullary shunting after ischaemia and reperfusion in the porcine kidney?

Background: Renal perfusion may redistribute from cortex to medulla during systemic hypovolaemia and after renal ischaemia for other reasons, but there is no consensus on this matter. We studied renal perfusion after renal ischaemia and reperfusion.

Methods: Renal perfusion distribution was examined by use of Gadolinium-labeled microspheres (MS) after 2 h (hrs) and 4 h ischaemia of the pig kidney followed by 4 h of reperfusion.

Use of plasma clearance of technetium Tc 99m pentetate to estimate renal clearance during postnatal development in pigs.

Objective: To compare renal clearance of technetium Tc 99m pentetate with plasma clearance by use of a glomerular filtration rate technique in pigs from 3 to 24 weeks of age.

Animals: 24 female pigs.

Procedure: At the time of investigation, 5 pigs were 3 weeks old, 6 pigs were 6 weeks old, 8 pigs were 12 weeks old, and 5 pigs were 24 weeks old.