Publications by authors named "Lene Drasbek Huusom"

Objective: Congenital heart disease (CHD) is the most common type of congenital birth defect, but little is known about possible modifiable behavioral risk factors. The study aimed to assess whether intake of periconceptional or postconceptional multivitamin was associated with a decreased risk of CHD in the offspring.

Study Design: The study population comprised 15,567 women from the Copenhagen Pregnancy Cohort with complete data on multivitamin intake before and during pregnancy, who gave birth to live-born singletons from October 2012 to October 2016.

View Article and Find Full Text PDF

Objectives: To compare mortality, morbidity and neurodevelopment by mode of delivery (MOD) for very preterm births with low prelabour risk of caesarean section (CS).

Methods: The study was a population-based prospective cohort study in 19 regions in 11 European countries. Multivariable mixed effects models and weighted propensity score models were used to estimate adjusted odds ratios (aOR) by observed MOD and the unit's policy regarding MOD.

View Article and Find Full Text PDF

Children born preterm have an increased risk of severe morbidity, e.g. cerebral palsy (CP), compared to children born at term.

View Article and Find Full Text PDF

Introduction: The aim of this study was to assess the association between multivitamin intake during pregnancy and the risk of preterm birth and very preterm birth.

Methods: The study population comprised 15,629 women from the Copenhagen Pregnancy Cohort with data on pregnancy multivitamin intake during their first trimester who gave birth to singletons from October 2012 to October 2016. Data on pregnancy multivitamin intake were linked to the Medical Birth Registry to identify the birth outcome.

View Article and Find Full Text PDF

Importance: Administration-to-birth intervals of antenatal corticosteroids (ANS) vary. The significance of this variation is unclear. Specifically, to our knowledge, the shortest effective administration-to-birth interval is unknown.

View Article and Find Full Text PDF

Objective: Women with early cervical cancer or intraepithelial neoplasia grades 2 and 3 (CIN2+) are treated by conization; however, they still have a higher risk for subsequent CIN2+ than the general female population. Persistence of high-risk (HR) human papillomavirus (HPV) is a key factor in the development of CIN2+. We investigated persistence and reappearance of type-specific HR HPV infection after conization and evaluated possible co-factors.

View Article and Find Full Text PDF

Objective: To examine period-, age- and histology-specific trends in the incidence rate of borderline ovarian tumors in Denmark in 1978-2006.

Design: Register-based cohort study.

Setting: Denmark 1978-2006.

View Article and Find Full Text PDF

Introduction: Ovarian cancer (OC) registrations in the Danish Cancer Registry (CR) and the Danish Pathology Data Bank (PDB) 1978-99 were compared in order to assess the possibility of identifying OC cases from another data source than the CR.

Material And Methods: A total of 13,320 OC were identified in the CR/PDB and comparisons of the registrations were performed.

Results: The frequency of cases registered in both registries increased during 1978-99.

View Article and Find Full Text PDF

Objective: The aim was to examine risk factors for ovarian borderline tumors overall, and according to histological subtype (serous vs. mucinous), in a large Danish population-based case-control study.

Methods: Ovarian borderline cases and controls were recruited from 1995 to 1999, and personal interviews were conducted.

View Article and Find Full Text PDF

Background: The Nordic countries are well-known high-incidence areas of ovarian cancer, but even within the Nordic countries, differences exist.

Methods: Focus in this descriptive epidemiological study is to assess developments in incidence and mortality of ovarian cancer in Denmark 1978-2002 and to make a comparison with the development in the other Nordic countries. The results are based on data from the nationwide Danish Cancer Registry as well as the other Nordic Cancer Registries.

View Article and Find Full Text PDF

Background: A European multicenter study (Surveillance of Cerebral Palsy in Europe, SCPE) was used to describe changes over time in multiple birth rates and cerebral palsy (CP) rates among multiple born infants, to compare CP rates and clinical types between multiples and singletons, and to analyse the influence of birth order in twins.

Methods: Data were collected from 12 European population-based CP registers on 6613 children born in 1975-90, as well as demographic data.

Results: The rate of multiple birth in the populations increased from 1.

View Article and Find Full Text PDF