Antiarthritic and Antinociceptive Properties of Ylang-Ylang () Essential Oil in Experimental Models.

The aim of this study was to evaluate the effect of ylang-ylang () essential oil (YEO) on models of experimental arthritis, persistent inflammation, and nociception in mice. YEO treatment at doses of 100 and 200 mg/kg reduced the infiltration of leukocytes into the joint cavities of mice submitted to zymosan-induced arthritis 6 h and 7 days after arthritis induction. At these doses, YEO treatment reduced the formation of joint edema 4 and 6 h after arthritis induction, and at a dose of 200 mg/kg, YEO treatment reduced mechanical hyperalgesia 3 and 4 h after arthritis induction.

1,4-Diaryl-1,2,3-triazole neolignan-celecoxib hybrids inhibit experimental arthritis induced by zymosan.

Rheumatoid arthritis (RA) is a chronic autoimmune disease that causes cartilage damage. Anti-inflammatories are widely used in the management of RA, but they can have side effects such as gastrointestinal and/or cardiovascular disorders. Studies published by our group showed that the synthesis of hybrid triazole analogs neolignan-celecoxib containing the substituent groups sulfonamide (L15) or carboxylic acid (L18) exhibited anti-inflammatory activity in an acute model of inflammation, inhibited expression of P-selectin related to platelet activation and did not induce gastric ulcer, minimizing the related side effects.

Bioclimatic and Landscape Factors drive the Potential Distribution of , and (Hemiptera, Aphrophoridae) in Southeastern Iberian Peninsula.

and are the main vectors of the invasive bacteria and key threats to European plant health. Previous studies of the potential distribution of reveal that climatic factors are the main drivers of its distribution on the Mediterranean Basin scale. Other local studies reveal that the landscape could also have a role in the distribution of both species of and .

Analgesic and anti-inflammatory potential of ethanolic extract from Serjania erecta leaves.

Ethnopharmacological Relevance: The infusion of Serjania erecta Radlk (Sapindaceae) (popular name "cipó-cinco-folhas") leaves is used in popular medicine to treat back pain. The anti-inflammatory, anti-hyperalgesic and anti-nociceptive properties of the ethanolic extract from S. erecta leaves (EESE) has not been yet completely clarified.

Analgesic and Anti-Inflammatory Properties of Ethanolic Extract of Leaves.

Nonclinical trials are important to validate the efficacy and safety of medicinal plants. Scientific toxicological studies with Yuncker have showed its safety; however, no studies have indicated the analgesic or antiarthritic potential of the ethanolic extract of leaves (EEPV). The objective of the present work was to evaluate the antiarthritic and antinociceptive effects of EEPV in experimental mouse models.

Practical Update of the Guidelines Published by the Psoriasis Group of the Spanish Academy of Dermatology and Venereology (GPs) on the Treatment of Psoriasis With Biologic Agents: Part 2 - Management of Special Populations, Patients With Comorbid Conditions, and Risk.

Background And Objectives: Since its inception, the Psoriasis Group (GPs) of the Spanish Academy of Dermatology and Venereology (AEDV) has worked to continuously update recommendations for the treatment of psoriasis based on the best available evidence and incorporating proposals arising from and aimed at clinical practice. An updated GPs consensus document on the treatment of moderate to severe psoriasis was needed because of changes in the treatment paradigm and the approval in recent years of a large number of new biologic agents.

Methodology: The consensus document was developed using the nominal group technique complemented by a scoping review.

Lantana canescens (Kunth) inhibits inflammatory and hyperalgesic responses in murine models.

Ethnopharmacological Relevance: Lantana canescens is popularly known in Brazil as "cidreirinha" or "chumbinho-branco". It is found in Pantanal biome and its flowers and leaves are used in traditional medicine to treat pain and inflammation. Information about this species is limited to the activity of isolated essential oils.

Macrophage activation in vitro by Parachartergus fraternus venom.

Parachartergus fraternus wasp induces inflammation with a predominance of mononuclear cells, that can acquire macrophage functions at the sting site, amplifying the response. These cells can be activated by venomous animals and are involved in destruction of injurious agents and release of inflammatory mediators. The objective of this work was to evaluate the activity of P.

First record of the Granulate Ambrosia Beetle, (Coleoptera: Curculionidae, Scolytinae), in the Iberian Peninsula.

The Granulate Ambrosia Beetle Xylosandrus crassiusculus, an alien species of Asian origin, was recorded for first time in the Iberian Peninsula. Many specimens were collected in October 2016 in the Valencia region (Spain) from infested carob trees. The species is included in the EPPO Alert List as causing serious damage in many Mediterranean regions.

Saproxylic community, guild and species responses to varying pheromone components of a pine bark beetle.

Some bark beetle species (Coleoptera: Scolytinae) produce aggregation pheromones that allow coordinated attack on their conifer hosts. As a new saproxylic habitat is founded, an assemblage of associated beetles kairomonally respond to bark beetle infochemicals. Ips sexdentatus is one of the major damaging insects of Pinus spp.