Publications by authors named "Lena Podlovny"
The yin and yang of corpus luteum-derived endothelial cells: balancing life and death.
Domest Anim Endocrinol
August 2005
Article Synopsis
- The corpus luteum (CL) is richly supplied with blood vessels, facilitating communication between steroidogenic and endothelial cells, which is crucial for CL function.
- Endothelin-1 (ET-1), linked to luteolytic hormone PGF2alpha, has been identified as a key player in the regulation of the CL, impacting the expression of receptors and enzymes in luteal endothelial cells (LEC).
- Factors that promote blood vessel growth, such as PGF2alpha, enhance LEC proliferation and survival, highlighting their importance in maintaining normal CL activity and suggesting a complex interplay between vascular and hormonal signals during the CL life-span.