Prophylactic treatment of breast implants with a solution of gentamicin, vancomycin and cefazolin antibiotics for women undergoing breast reconstructive surgery: protocol for a randomised, double-blind, placebo-controlled trial (The BREAST-AB trial).

Introduction: Periprosthetic infection is one of the most severe complications following implant-based breast reconstruction affecting 5%-10% of the women. Currently, many surgeons apply antibiotics locally on the breast implant to reduce the risk of postoperative infection, but no randomised, placebo-controlled trials have tested the treatment's efficacy.

Methods And Analysis: The BREAST-AB trial (BREAST-AntiBiotics) is an investigator-initiated, multicentre, randomised, placebo-controlled, double-blind trial of local treatment with gentamicin, vancomycin and cefazolin on breast implants in women undergoing implant-based breast reconstruction.

[Breast implant rupture can mimic disseminated cancer].

Silicone-induced granuloma is a well-known, but rare delayed complication of implantation of silicone breast prostheses and consists of a foreign body reaction with encapsulation of free silicone, most often due to implant rupture with silicone leakage. We present a case report of a patient with a silicone-induced granuloma. On a PET/CT silicone-induced granuloma can mimic disseminated cancer.

[Breast asymmetry inadolescent girls can be caused by large benign tumours].

This is a case report of a 14-year-old female with a giant juvenile fibroadenoma in her right breast. She successfully underwent surgical excision with simultaneous breast lift and reconstruction using a modified Goldilocks procedure. We want to address the importance of referring patients with breast asymmetry to surgical assessment and furthermore advocate for considering use of reconstructive techniques or conferring with a plastic surgeon when removing these large tumours in order to achieve a more aesthetically beautiful and symmetric result.

Dermal nipple-areola complex flap method in female to male gender affirming surgery.

Subcutaneous mastectomy plays a major role in female to male (FtM) gender affirming surgery, and obtaining a flattering chest contour remains a challenge to the surgeon. We present an operative method using a dermal nipple-areola complex (NAC) flap, with the aim to create a naturally masculine appearance, while reducing the risk of NAC complications by maintaining sufficient neurovascularisation. This case report describes how the novel approach may potentially be applied as an alternative to the traditionally performed free nipple graft technique in FtM gender confirming surgery.