Publications by authors named "Lena Bjorck"
Background: There is insufficient evidence to provide recommendations for leisure-time physical activity among workers across various occupational physical activity levels. This study aimed to assess the association of leisure-time physical activity with cardiovascular and all-cause mortality across occupational physical activity levels.
Methods: This study utilized individual participant data from 21 cohort studies, comprising both published and unpublished data.
Objective: Health effects of different physical activity domains (ie, during leisure time, work and transport) are generally considered positive. Using data, we assessed independent associations of occupational and leisure-time physical activity (OPA and LTPA) with all-cause mortality.
Design: Two-stage individual participant data meta-analysis.
Article Synopsis
- - The study analyzed the relationship between alcohol consumption and metabolic syndrome (MetS) using data from 3,051 adults in the Swedish INTERGENE cohort, identifying different definitions of MetS (ATP III, IDF, JIS) and their varying prevalence rates.
- - Results indicated that medium to high alcohol consumption was linked to lower odds of MetS, while abstainers showed no significant differences; prevalence estimates for MetS ranged from 13.9% to 25.3%, with men generally being more affected than women.
- - The findings suggest that the impact of alcohol on MetS varies depending on the definition used, specifically that those meeting the strictest MetS criteria (ATP III) might actually benefit from
Background: Stroke is a common and severe disease that requires prompt care. Symptom expressions as one-sided weakness and speech difficulties are common and included in public stroke campaigns. For some patients stroke can present with subtle and less common symptoms, difficult to interpret.
View Article and Find Full Text PDFIt is unclear how increasing body mass index (BMI) influences risk of cancer in young women. We used data from the Medical Birth, Patient and Cause of Death registers collected between 1982 and 2014 to determine the risk of obesity-related cancer types, breast cancer, all cancer and cancer-related death in relation to BMI in 1,386,725 women, aged between 18 and 45 years, in Sweden. During a median follow-up of 16.
View Article and Find Full Text PDFAims: To assess the long-term risk of developing type 2 diabetes in patients with obesity who have undergone gastric bypass surgery compared to non-operated patients with obesity and the general population.
Methods: This study included 71,495 patients aged 20-65 years with a principal diagnosis of obesity in the Swedish Patient Register in 2001-2013. Of these, 23,099 had undergone gastric bypass and 32,435 had not.
Article Synopsis
- Venous thromboembolism (VTE) is a common complication during acute COVID-19, but the long-term risk associated with it remains unclear.
- This study focused on Swedish individuals aged 18-84 who were either hospitalized or tested positive for COVID-19, comparing their VTE rates to a matched control group without COVID-19.
- Results showed that hospitalized COVID-19 patients had significantly increased long-term risks for pulmonary embolism (PE) and deep venous thrombosis (DVT), while non-hospitalized individuals had similar VTE risks as those without COVID-19.
Article Synopsis
- Type 2 diabetes significantly increases the risk of hospitalization, intensive care, and death from COVID-19, while the risks for type 1 diabetes are less pronounced and diverging.
- The study analyzed data from over half a million diabetes patients in Sweden, adjusting for age, socioeconomic factors, and other conditions to assess the impacts of diabetes on COVID-19 outcomes.
- Results show that while type 1 diabetes patients had a higher chance of hospitalization, they did not face increased risks for ICU care or death compared to those without diabetes.
Article Synopsis
- Adolescent obesity significantly increases the risk of developing type 2 diabetes later in life, with notably higher risks for those with a BMI of 35 kg/m or more.
- A study involving over 1.6 million men showed that higher adolescent BMI corresponds to earlier onset of diabetes and worsened metabolic control.
- The findings indicate that young men with greater BMI not only face a higher chance of diabetes diagnosis but also experience more complications, like increased HbA1c levels and higher albuminuria rates.
Aim: We aim to assess the risk of heart failure in patients with obesity with and without gastric bypass surgery compared with population controls.
Methods And Results: This cohort study included all patients aged 20-65 years with a first ever registered principal diagnosis of obesity in the Swedish Patient Register in 2001-2013. These patients were matched by age, sex, and region with two population controls from the general Swedish population without obesity diagnosis.
Aims: To compare trends in short-term and long-term survival of patients with heart failure (HF) compared with controls from the general population.
Methods And Results: We used data from the Swedish National Inpatient Registry to identify all patients aged ≥18 years with a first recorded diagnosis of HF between 1 January 1987 and 31 December 2014 and compared them with controls matched on age and sex from the Total Population Register. We included 702 485 patients with HF and 1 306 183 controls.
Aims: The aim of this study was to investigate the relation between body mass index (BMI) in young women, using weight early in pregnancy as a proxy for pre-pregnancy weight, and risk for early cardiovascular disease (CVD) and mortality.
Methods And Results: In this prospective, registry-based study, we used weight data in early pregnancy from women, registered in the Swedish Medical Birth Registry, and who gave birth between 1982 and 2014 (n = 1,495,499; median age 28.3 years).
Aims: Atrial fibrillation (AF) is associated with arterial thromboembolism, mainly ischaemic stroke, while venous thromboembolism (VTE) in AF is less well studied. The aim of this study, therefore, was to examine the relationship between AF and VTE, including pulmonary embolism (PE) and deep venous thrombosis (DVT).
Methods And Results: AF cases without previous VTE, ischaemic stroke or pulmonary arterial hypertension were identified from the Swedish Inpatient Registry between 1987 and 2013 and compared to two population controls per case without AF matched for age, sex, and county with respect to the incidence of VTE, PE, and DVT.
Objective: The aim of this study was to estimate risks of myocardial infarction, ischemic stroke, and cardiovascular-related and all-cause mortality after Roux-en-Y gastric bypass (RYGB) for obesity compared with nonop-erated obese patients and matched nonobese population controls.
Background: Few studies have assessed the influence of RYGB on fatal and non-fatal myocardial infarction and ischemic stroke, and the results vary between studies.
Method: All patients aged 20 to 65 years with obesity diagnosis in the nationwide Swedish Patient Registry in 2001 to 2013 were included.
Obesity rates in adolescence and young adulthood have increased in Sweden, reflecting global trends. To which extent this occurs across different socioeconomic strata has not been clarified. The aim of the present study was to investigate trends in social inequalities in body mass index (BMI) in young/mid-adulthood Swedish women.
View Article and Find Full Text PDFIntroduction: In type 1 diabetes, potential loss of life-years is greatest in those who are youngest at the time of onset. Using data from a nationwide cohort of patients with type 1 diabetes, we aimed to study risk factor trajectories by age at diagnosis.
Research Design And Methods: We stratified 30 005 patients with type 1 diabetes aged 18-75 years into categories based on age at onset: 0-10, 11-15, 16-20, 21-25, and 26-30 years.
Background: Incidence rates of cardiomyopathies, which are a common cause of heart failure in young people, have increased during the last decades. An association between body weight in adolescence and future cardiomyopathy among men was recently identified. Whether or not this holds true also for women is unknown.
View Article and Find Full Text PDFBackground Body mass index (BMI) may be a stronger risk factor for heart failure than for coronary heart disease in type 2 diabetes mellitus, but prior studies have not been powered to investigate the relative and absolute risks for acute myocardial infarction and heart failure in type 2 diabetes mellitus by BMI and glycemic level combined as compared with age- and sex-matched general population comparators. Methods and Results We identified 181 045 patients from The Swedish National Diabetes Registry, registered during 1998 to 2012 and 1538 434 general population comparators without diabetes mellitus, matched for age, sex, and county, all without prior major cardiovascular disease. Cases and comparators were followed with respect to the outcomes through linkage to the Swedish Inpatient Registry.
View Article and Find Full Text PDFBackground: Secondary prevention after an acute myocardial infarction (AMI) reduces morbidity and mortality, but suboptimal secondary prevention of cardiovascular disease is common. Therefore, the present study aimed to identify potential underlying factors for suboptimal secondary prevention 2 years after an AMI event.
Methods: Patients aged 18-85 years at the time of their index AMI and hospitalized between July 2010 and December 2011, were identified retrospectively and consecutively from hospital discharge records.
Article Synopsis
- - A study in Sweden found a rising trend of heart failure (HF) among younger women, despite a decrease in older populations, prompting an investigation into the link between body mass index (BMI) and hospitalization for HF.
- - Researchers analyzed data from over 1.3 million women aged 18-45 who gave birth between 1982 and 2014, tracking their hospitalization rates for HF using national health registers.
- - Results indicated that higher BMI significantly increased the risk of HF, with women classified as obese (BMI ≥ 35 kg/m) having nearly a five-fold higher risk compared to those with a normal BMI, highlighting the importance of weight management for heart health.
Objective: Low weight has been associated with increased mortality risks in type 1 diabetes. We aimed to investigate the importance of weight and weight gain/loss in the Swedish population diagnosed with type 1 diabetes.
Research Design And Methods: Patients with type 1 diabetes ( = 26,125; mean age 33.
Objective: Chest pain is the predominant symptom in patients with acute myocardial infarction (AMI). A lack of chest pain in patients with AMI is associated with higher in-hospital mortality, but whether this outcome is sustained throughout the first years after onset is unknown. Therefore, we aimed to investigate long-term mortality in patients hospitalised with AMI presenting with or without chest pain.
View Article and Find Full Text PDFBackground Atrial fibrillation is associated with hyperthyroidism. Patients with primary aldosteronism have an increased prevalence of atrial fibrillation. However, the prevalence of primary aldosteronism in the atrial fibrillation population is unknown.
View Article and Find Full Text PDFObjective: Type 2 diabetes is strongly associated with obesity, but the mortality risk related to elevated body weight in people with type 2 diabetes compared with people without diabetes has not been established.
Research Design And Methods: We prospectively assessed short- and long-term mortality in people with type 2 diabetes with a recorded diabetes duration ≤5 years identified from the Swedish National Diabetes Register (NDR) between 1998 and 2012 and five age- and sex-matched control subjects per study participant from the general population.
Results: Over a median follow-up of 5.
Unlabelled: Background A large body size in early adult life has been associated with an increased risk of atrial fibrillation (AF) later in life in men; however, this has not yet been investigated in women.
Design: Prospective cohort study.
Methods: We included all women in the Swedish Medical Birth Registry with known weight and height from 1982 to 2014.