Publications by authors named "Lena Bielawska"
Effect of statins on bone turnover markers in postmenopausal women: a pilot study.
Postepy Kardiol Interwencyjnej
December 2023
Article Synopsis
- Lower bone mineral density (BMD) is commonly found in inflammatory bowel disease (IBD) patients, and this study focused on the effects of folic acid levels and MTHFR gene polymorphism on BMD in Crohn's disease (CD) and ulcerative colitis (UC) patients compared to healthy controls.
- The analysis showed that IBD patients had significantly lower BMD, T-scores, and Z-scores in both the lumbar spine and femoral neck than the control group, indicating a higher risk for low BMD.
- Although no notable differences in folic acid levels were found between groups, the study suggested that certain MTHFR gene polymorphisms might influence bone density in IBD patients,
Obesity, currently defined as a disease, is associated with a number of metabolic disorders, and oxidative stress is discussed as the link between them. The aim of this study was to analyze the plasma markers reflecting oxidative modification of lipids and lipoproteins, oxidized LDL (oxLDL) and thiobarbituric acid reactive substances (TBARS), under the influence of the 75 g of oral glucose during oral glucose tolerance test (OGTT), in patients with increased body mass. One hundred twenty individuals of both genders (46 women and 74 men) aged 26 to 75 years with increased body mass (BMI > 25 kg/m) were recruited for the study.
View Article and Find Full Text PDFThere is growing evidence that obstructive sleep apnoea (OSA) influences the hypothalamic-pituitary-gonadal axis (HPG axis) in men. The aim of the study was to assess the association of nesfatin-1 with HPG axis disturbances in OSA. This is a prospective study with consecutive enrolment.
View Article and Find Full Text PDFThe aim of the study was the assessment of the impact of supplementation with folic acid on the concentration of homocysteine, total cholesterol (TC), HDL- and LDL-cholesterol, triglycerides (TG), apoprotein AI (apoAI) and apoprotein B (apoB) in patients suffering from primary hypertension. The examined group comprised 42 patients suffering from primary hypertension. All examined patients underwent laboratory tests as follows: concentration of homocysteine, folic acid, TC, LDL-cholesterol, HDL-cholesterol, TG, apoAI and apoB.
View Article and Find Full Text PDFINTRODUCTION There is an inverse relationship between high‑density lipoprotein cholesterol (HDL-C) levels and the risk of atherosclerosis. OBJECTIVES The aim of the present study was to assess the oxidant-antioxidant balance in elderly people with different concentrations of HDL-C. PATIENTS AND METHODS A total of 541 people aged 60 years or older were examined, of whom 90 individuals with no acute or severe chronic disorders had their waist circumference, body mass index, percentage of body fat, and blood pressure measured.
View Article and Find Full Text PDFUnlabelled: The results of epidemiological and clinical tests have shown that in patients with primary arterial hypertension, a chronic mild inflammation develops. The purpose of the study was to determine whether administration of folic acid to patients with primary arterial hypertension influences concentrations of indicators of inflammation: hsCRP, sICAM-1 and sVCAM-1.
Material And Methods: The examination was carried out in 41 patients with primary arterial hypertension, aged 19-65 (21 men and 20 women), without complications of hypertension and/or coexisting diseases.