Publications by authors named "Lemuel R Non"

Background: Preventive strategies for cytomegalovirus (CMV) in the posttransplant period have changed the pattern of CMV infections, now more commonly manifesting as late-onset occurrences known as post-prophylaxis delayed-onset CMV disease (PPDOC). We conducted a survey to investigate provider practices in managing PPDOC.

Methods: A web-based provider survey on the management of PPDOC was developed using Research Electronic Data Capture (REDCap).

View Article and Find Full Text PDF

Chat Generative Pre-trained Transformer (ChatGPT), the flagship generative artificial intelligence (AI) chatbot by OpenAI, is transforming many things in medicine, from healthcare and research to medical education. It is anticipated to integrate in many aspects of the medical industry, and we should brace for this inevitability and use it to our advantage. Here are proposed ways you can use ChatGPT in medicine with some specific use cases in antimicrobial stewardship and hospital epidemiology.

View Article and Find Full Text PDF

Infectious gastroenteritis is common after transplantation and can lead to increased morbidity and mortality. A wide range of organisms can lead to gastroenteritis in this patient population. Clostridioides difficile, cytomegalovirus, and norovirus are the most common pathogens.

View Article and Find Full Text PDF
Article Synopsis
  • Non-Candida opportunistic yeasts, particularly Pseudozyma, are increasingly causing bloodstream infections (BSIs) in people with weakened immune systems, like stem cell transplant (SCT) recipients.
  • The first known case of Pseudozyma BSI in a SCT recipient exhibited skin involvement, challenging previous understandings, and the patient was successfully treated after failing to respond to standard echinocandin therapy like micafungin.
  • A review of SCT recipients over 15 years found additional cases of non-Candida yeast BSIs, highlighting the need for clinicians to be alert to the possibility of these resistant fungi in patients receiving echinocandin medications.
View Article and Find Full Text PDF

Antiretroviral therapy has revolutionized the care of people with human immunodeficiency virus (HIV) by reducing morbidity and mortality from acquired immunodeficiency syndrome-related conditions. Despite longer life expectancy, however, HIV-infected individuals continue to have a higher risk of death compared with the general population. This has been attributed to the increasing incidence of noncommunicable diseases, in particular, atherosclerotic cardiovascular diseases.

View Article and Find Full Text PDF

Background: Staphylococcus lugdunensis is a coagulase-negative staphylococcus with similar virulence characteristics as Staphylococcus aureus. Whether S. lugdunensis causes infective endocarditis (IE) in a similar proportion of cases as S.

View Article and Find Full Text PDF

Hemophagocytic lymphohistiocytosis (HLH) and rhabdomyolysis are rare complications of typhoid fever from Salmonella enterica serovar Typhi. Herein, we describe the clinical features in a 21-year-old female from India who presented to the intensive care unit with fever, severe pancytopenia, and rhabdomyolysis.

View Article and Find Full Text PDF

We report two cases of bacteremia with Actinobaculum schaalii, a rarely reported, anaerobic, Gram-positive bacterium. The first case was a patient with renal cancer who developed pyelonephritis after cryoablation, and the second was a patient who developed sepsis after a urogenital procedure. Bacteremia resolved after administration of empiric antibiotic therapy.

View Article and Find Full Text PDF