Clinical characteristics and course in patients with high titer anti-RNP antibodies.

Forty-four patients with high titers of anti-RNP antibodies, without anti-Sm or anti-nDNA antibodies, were studied retrospectively for clinical symptomatology, morbidity and mortality. Seven had died. Eleven had renal disease.

Furcal defects in dry mandibles. Part II: Severity of furcal defects.

Two hundred and eighty two first and second molar teeth from 100 dry mandibles of South African Negro skulls were scored by four degrees of severity of furcal involvement. The severity was judged by whether the furca was involved from one or both sides, by the depth of the defect on each side and by the sum of the depths of the defects on both lingual and buccal sides. Analysis of the frequencies of the scores show that: (1) First molars are more severely affected than second molars; (2) There is a general trend of scores 1 and 2 (normal and mild involvement) to be predominant in the 3rd decade of life, while by the 5th, 6th and 7th decades scores 3 and 4 (moderate and severe involvement) predominate; (3) The difference between the frequencies of all the scores for the right and left sides was not significant.

Clinical and histological changes following cryotherapy in a case of widespread oral leukoplakia.

The effects of cryotherapy on widespread leukoplakia of the buccal and vestibular mucosa were observed clinically and studied histologically. The treated areas were clinically normal 2 months after treatment, and discomfort and inconvenience of treatment were minimal. The epithelium, which was initially orthokeratinized, with mild dysplasia, and which was almost entirely lacking in glycogen, reverted to the parakeratinized or non-keratinized form, with normal distribution of glycogen in the stratum spinosum.

Coexistence of HLA-B27 ankylosing spondylitis and DR4 seropositive nodular rheumatoid arthritis in patient with membranous nephropathy.

A case of definite ankylosing spondylitis (AS), classical rheumatoid arthritis (RA) and membranous nephropathy is presented. Concurrent presence of the HLA-B27 and HLA-DR4 antigens was demonstrated. The association of AS and RA as well as RA and membranous nephropathy are discussed and the literature reviewed.

Osteosarcoma in a patient with Hutchinson-Gilford progeria.

A 13-year-old female with Hutchinson-Gilford progeria, who developed an osteosarcoma of the right chest wall, is reported. This is the first reported association of a malignant neoplasm with this syndrome.

The measurement of jaw movement. Part II.

To summarize, the principles and the application of an apparatus have been described which without appreciable physical restraint provides graphic representations of the movements of a point on the mandible in three conventional anatomic planes-sagittal, coronal, and horizontal. The apparatus also provides data which permit an estimation of the magnitude and direction of movement of a point on the jaw during function in relation to time. This information prepares the way for the calculation of the path of the selected point in space, as well as its mean velocity and acceleration.

The measurement of jaw movement. Part I.

A new method of recording the movements of a point on the mandible appears to be a valuable addition to the many means which are available for attempting to fathom the secrets of jaw movements. While in its present form this method does not fully describe any of the movements of the jaws, the over-all patterns recorded may be of significance.