Poor sleep quality and associated factors among community-dwelling older adult at Gondar town.

Sleep disturbance poses a significant health concern for older adults, as it is associated with overall health decline. Poor sleep quality increases the risk of chronic diseases, depression, anxiety, and diminished quality of life. Therefore, this study aimed to assess the prevalence of poor sleep quality and its associated factors among older adults living in the community of Gondar town, Northwest Ethiopia, in 2023.

Spatial distribution and determinants of early postnatal discharge among vaginally delivered mothers in Ethiopia: spatial and multilevel analysis of Ethiopian demographic survey data.

Background: Postnatal hospital care is aimed to detect any complications for both mother and child. Postnatal care should start as early as possible, especially during the first 24 hours. No study assessed the hotspot areas of early postnatal discharge and its community and individual level determinants in Ethiopia.

Receptor tyrosine kinases and steroid hormone receptors in breast cancer: .

Breast cancer development and progression are driven by intricate networks involving receptor tyrosine kinases (RTKs) and steroid hormone receptors specifically estrogen receptor (ER) and progesterone receptor (PR). This review examined roles of each receptor under normal physiology and in breast cancer, and explored their multifaceted interactions via signaling pathways, focusing on their contributions to breast cancer progression. Since defining the mechanism by which these two-receptor mediated signaling pathways cooperate is essential for understanding breast cancer progression, we discussed the mechanisms of cross-talk between RTKs and ER and PR and their potential therapeutic implications as well.

Posttraumatic stress disorder and its associated factors among people living in Dabat district, northwest Ethiopia.

Background: The conflict between the Ethiopian government and the Tigray People's Liberation Front (TPLF) in the Dabat district of Ethiopia has led to significant civilian casualties, instances of rape, sexual abuse, and property theft. These traumatic events contribute to the development of post-traumatic stress disorder (PTSD) among local residents. However, there is currently no available data on the prevalence of PTSD and its associated factors in this region.

Brain functional connectivity in hyperthyroid patients: systematic review.

Introduction: Functional connectivity (FC) is the correlation between brain regions' activities, studied through neuroimaging techniques like fMRI. It helps researchers understand brain function, organization, and dysfunction. Hyperthyroidism, characterized by high serum levels of free thyroxin and suppressed thyroid stimulating hormone, can lead to mood disturbance, cognitive impairment, and psychiatric symptoms.