Antitumor effect of bromo-naphthoquinone associated with tannic acid in triple negative breast cancer cells.

Triple-negative breast cancer (TNBC) is an aggressive type of tumor that tends to recur in women. It is characterized by the absence of hormonal receptors, making it challenging to diagnosis and treatment. In this study, we investigated the anti-tumor effects of a pro-oxidant naphthoquinone derivative called bromo-naphthoquinone (BrNQ) isolated and combined with the antioxidant tannic acid (TA) in order to improve treatment.

Energy utilization and requirement of broiler breeders during the production phase.

This study aimed to evaluate energy utilization and propose models for metabolizable and net energy requirements in broiler breeders during the egg production phase. Sixty Cobb500 broiler breeders aged between 29 and 65 wk were randomly assigned to 3 feeding levels. At each age, 6 birds were adapted for 8 d to 3 levels of metabolizable energy intake (MEi), established based on the amount of feed allocated: 1) the amount of feed recommended in the guideline, 2) 25% above, and 3) 25% below.

Description and Validation of Flow-Through Chambers of Respirometry for Measuring Gas Exchange in Animal Trials.

Indirect calorimetry (IC) is a widely used method to study animal energy metabolism by measuring gas exchange. The accuracy of IC depends on detecting variations in signals reflecting the metabolic response, which can be challenging due to measurement noise and external factors. This study proposes a methodology to validate IC systems, including an easy-to-use spreadsheet for data computing, to verify accuracy and detect whole-system leaks.

The Response to Dietary Leucine in Laying Lens.

This study aimed to estimate the standardized ileal digestible leucine intake (SID-Leu, mg) in laying hens for maintenance, and to describe the response in laying hens to SID-Leu, thereby providing the information required to determine the optimum economic intake of SID-Leu for laying hens. Two nitrogen balance series, one balanced and the other unbalanced with respect to leucine (Leu), were used to estimate the SID-Leu requirement for maintenance using 36 roosters per series. The roosters were randomly distributed among the six levels of Leu with each level being replicated six times.

Composition of feathers and pulp of two broiler genotypes.

1. Cobb and Ross broilers (200 of each sex and breed) were fed four phases of diets formulated with balanced protein to match their amino acid requirements throughout growth. Ten birds per genotype were sampled and euthanised at two-weekly intervals from 14 to 112 d of age.

A Sensorized Overground Body Weight Support System for Assessing Gait Parameters During Walking Rehabilitation.

Although the needs of individuals undertaking gait rehabilitation sessions may appear similar, they present facets that may assist therapists to come up with more targeted treatment. However, acquiring such aspects is a major problem for rehabilitation personnel due to time constraints and/or complexity. In this paper, we propose an alternative method for estimating gait parameters for individuals requiring Body Weight Support (BWS) during gait training.

Estimating Range of Lower Body Joint Angles with a Sensorized Overground Body-Weight Support System.

Recent trends in rehabilitation and therapy are turning to data-driven approaches to personalize treatment. Due to such approaches, data collection methods have become more complex and expensive, in terms of financial resources, technological knowledge, and time required to implement the data collection method. Such costs might deter clinical applications of otherwise good data collection methods.

Locomotion Synchronization and Gait Performance While Walking With an Overground Body Weight Support System.

Rehabilitation robotics offers new alternatives to patients and therapists to efficiently support walking training using Body Weight Support (BWS) systems. Automating the locomotion of overground BWS systems is one of the feasible approaches to free therapists from manual operation. However, the effect of locomotion control strategies of BWS system on participant's gait performance have not been studied sufficiently.

Effect of feed restriction on the maintenance energy requirement of broiler breeders.

Objective: This study aimed to evaluate the effect of the ad libitum and restricted feeding regimen on fasting heat production (FHP) and body composition.

Methods: Twelve Hubbard broilers breeders were selected with the same body weight and submitted in two feeding regimes: Restricted (T1) with feed intake of 150 g/bird/d and ad libitum (T2). The birds were randomly distributed on the treatments in two runs with three replications per treatment (per run).

Modelling Broiler Requirements for Lysine and Arginine.

Six assays were conducted to investigate male and female broiler responses to standardized ileal digestible (SID) lysine (Lys) and arginine (Arg). Response data were modeled to estimate the efficiency of utilization () of both amino acids and adjust factorial models to predict bird intake for SID Lys and SID Arg. In each assay, 1280 Cobb 500 broilers (640 male and 640 female) were randomly assigned to one of sixteen dietary treatments with four replicates of 20 birds.

A description of the growth and moulting of feathers in commercial broilers.

1. Changes in feather length and weight and daily losses of down, contour feathers, remiges and retrices were studied in two commercial broiler strains to determine feather growth and moult in broilers up to 112 d of age. 2.

A description of the potential growth and body composition of two commercial broiler strains.

1. The potential growth of feathers and feather-free body and their chemical components was measured in two commercial broiler strains. 2.

Efficiency of methionine and cystine utilization by broiler chickens using stable isotopes.

The aim of this study was to develop a method to determine the efficiency of utilization of Met and Cys using stable isotopes in order to reduce the number of sacrificed animals relative to the comparative slaughter technique. Met and Cys efficiencies were obtained separately and as total SAA values. Twenty-one 14- to 28-day-old broiler chickens were fed experimental diets containing different Met:Cys ratios (44:56, 50:50 and 56:44).

Optimal in-feed amino acid ratio for laying hens based on deletion method.

A total of 56 Hy-line W-36 hens from 28 to 30 weeks were used on nitrogen balance (NB) trial to estimate daily N maintenance requirements (NMR) and the genetic potential for daily N retention (NR T). The treatments consisted of six graded levels of nitrogen in the diets (N1 = 8; N2 = 16; N3 = 24; N4 = 32; N5 = 40; and N6 = 48 g N/kg of feed), formulated using the dilution technique. The regression analyses between nitrogen intake and excretion were performed to fit the exponential function and to determine the NMR = 292 mg/BW , which was applied for further calculation of NR T = 1,883 mg/BW .

Dental implants in patients with osteoporosis: a systematic review with meta-analysis.

There is currently no consensus regarding the survival rate of osseointegrated implants in patients with osteoporosis. A systematic review with meta-analysis was performed to evaluate the survival rate of implants in such patients. The PubMed/MEDLINE, Web of Science, Cochrane Library, and SciELO databases were used to identify articles published up to September 2016.

Risk perception and counselling among HIV-positive women in São Paulo, Brazil.

This study of HIV-positive women at a clinic for HIV/AIDS in São Paulo examined their risk perception for HIV before they had learned of their diagnosis and their experiences with pre- and post-test counselling. A sample of 148 women was interviewed regarding demographics, HIV risk factors and risk perception, pre- and post-test counselling, and sexual and reproductive conduct. The majority (77%) had been infected by their partners--37% by an injecting drug user partner.