Publications by authors named "Lele Huang"

Zeolites are used in the field of toluene nitrification reactions, but their intrinsic mechanism is not well explained. In this work, three typical zeolites including HZSM-5, HY, and Hβ are selected as catalysts and used for the nitration of toluene and typical monosubstituted benzenes with NO, and it explores the intrinsic influences on the nitrification of toluene on various zeolites through experimental and theoretical methods. The acidic properties and pore structures of three different zeolites were investigated through appropriate characterization techniques.

View Article and Find Full Text PDF

Light quality has significant effects on the growth and metabolite accumulation of algal cells. However, the related mechanism has not been fully elucidated. This study reveals that both red and blue light can promote the growth and biomass accumulation of , with the enhancing effect of blue light being more pronounced.

View Article and Find Full Text PDF

Background: Colonoscopy is essential for diagnosing colorectal diseases but can cause pain during the procedure. This study explored the analgesic effects of transcutaneous electrical nerve stimulation based on wrist-ankle acupuncture theory (TENS-WAA) in colonoscopy without anesthesia.

Methods: This prospective study included 120 participants undergoing colonoscopies without anesthesia.

View Article and Find Full Text PDF

Objective: As breast cancer cases rise globally, post-mastectomy lymphedema garners increasing scholarly attention. This study aims to conduct a comprehensive bibliometric analysis of Breast Cancer-Related Lymphedema (BCRL) research from 2003 to 2022, identifying trends and providing global research insights for future studies.

Method: The literature for this analysis was extracted from the Web of Science (WoS) Core Collection, encompassing 1199 publications, including 702 articles and 101 reviews, totaling 803.

View Article and Find Full Text PDF

Objective: Neck pain has emerged as a significant public health concern. This study is to unveil the present state of neck pain research, thereby furnishing invaluable insights for prospective research endeavours and clinical applications.

Methods: The study was initiated by searching the Web of Science Core Collection database, focusing on "neck pain".

View Article and Find Full Text PDF

Purpose: Low back pain (LBP) is a prevalent musculoskeletal disorder, and manual therapy (MT) is frequently employed as a non-pharmacological treatment for LBP. This study aims to explore the research hotspots and trends in MT for LBP. MT has gained widespread acceptance in clinical practice due to its proven safety and effectiveness.

View Article and Find Full Text PDF

Objective: The aims of this study were to develop the Ovarian-Adnexa Reporting and Data System (O-RADS) and O-RADS + contrast-enhanced ultrasound (O-RADS CEUS) scoring system to distinguish adnexal masses (AMs) and to compare the diagnostic efficacy of these systems with that of a magnetic resonance imaging scoring system (ADNEX MR).

Methods: We retrospectively evaluated 278 ovarian masses from 240 patients between May 2017 and July 2022. Pathology and adequate follow-up were used as reference standards for comparing the validity of O-RADS, O-RADS CEUS and ADNEX MR scoring to diagnose AMs.

View Article and Find Full Text PDF

Background: In this study, we used computed tomography (CT)-based radiomics signatures to predict the mutation status of KRAS in patients with colorectal cancer (CRC) and to identify the phase of radiomics signature with the most robust and high performance from triphasic enhanced CT.

Methods: This study involved 447 patients who underwent KRAS mutation testing and preoperative triphasic enhanced CT. They were categorized into training (n = 313) and validation cohorts (n = 134) in a 7:3 ratio.

View Article and Find Full Text PDF
Article Synopsis
  • This study evaluated the effectiveness of Tc-methoxy isobutyl isonitrile (MIBI) SPECT/CT myocardial perfusion imaging and cardiac magnetic resonance imaging (CMR) in diagnosing myocarditis in children based on various infection sources.
  • A total of 232 children were categorized into five groups based on their specific infections, with SPECT/CT showing higher positive rates for diagnosing myocarditis in viral and viral-mycoplasma infection groups; however, CMR performed better in viral-bacterial and bacterial-mycoplasma groups.
  • The study also indicated that while SPECT/CT did not significantly impact hospital costs, CMR-negative patients in certain infection groups tended to have higher average daily hospitalization costs
View Article and Find Full Text PDF

Purpose: To enhance tumor penetration by formulation design and tumor microenvironment (TME) modulation, herein a novel reactive oxygen species (ROS)-responsive size/shape transformable lipid-polymer hybrid nanoparticle (LPN) has been fabricated for the co-delivery of an anticancer and collagen-inhibition drug.

Methods: A ROS-responsive poly(D, L-lactide)-thioketal-polyethylene glycol (PLA-TK-PEG) co-polymer was synthesized. LPNs were then fabricated by encapsulation of losartan (LST)-loaded micelles as the core to support paclitaxel (PTX)-loaded liposomes.

View Article and Find Full Text PDF

Background And Purpose: Retina thickness has been studied in patients with neuromyelitis optica spectrum disorders (NMOSD) without distinguishing serostatus and limited data are available in unaffected eyes. We aimed to investigate retina thickness in eyes of aquaporin-4 immunoglobulin G antibody seropositive (AQP4-IgG) NMOSD patients with optic neuritis (AQP4-ON) and without (AQP4-NON).

Methods: Eligible studies were identified by searching PubMed and Embase.

View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to evaluate how dynamic metabolic curves and artificial neural network models can differentiate between nonspecific solitary pulmonary lesions using 18F-FDG PET multiphase imaging.
  • Researchers analyzed data from 71 patients (48 with malignant and 23 with benign lesions), collecting various metabolic parameters and using them to create prediction models based on diagnostic efficiency.
  • Results indicated that certain metabolic parameters and age were significant for distinguishing between lesion types, leading to the development of neural network models that improved diagnostic accuracy.
View Article and Find Full Text PDF

Purpose: To investigate the efficacy and safety of intra-arterial thrombolysis (IAT) in patients with central retinal artery occlusion (CRAO).

Methods: PubMed and EMBASE were searched for potentially eligible studies that reported IAT in CRAO patients from inception to Nov 8, 2021. Standard mean difference (SMD) was pooled to compare visual acuity (VA) at baseline with final in IAT patients.

View Article and Find Full Text PDF

Target of rapamycin (TOR) is a serine/threonine protein kinase that plays a central regulating role in cell proliferation, growth, and metabolism, but little is known about the TOR signaling pathway in . In this study, a DP-1 strain was isolated and identified, and its nutritional compositions were analyzed. Based on homologous sequence analysis, the conserved CsTOR protein was found in the genome of .

View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to evaluate blood flow perfusion images from renal dynamic imaging at various injection levels to create standards for injection quality and minimize misdiagnosis.
  • Data from 140 imaging scans were analyzed, categorizing them into four groups based on injection quality, with significant differences in imaging results across these groups.
  • Results indicated that poor injection quality led to unreliable images and high misdiagnosis rates, while better injection quality showed more consistent and accurate imaging outcomes.
View Article and Find Full Text PDF

Objective: This study aimed to investigate the correlation between best corrected visual acuity (BCVA) and retinal microstructural parameters detected by optical coherence tomography (OCT) in diabetic retinopathy macular edema (DRME).

Methods: Thirty-nine patients (64 eyes) with DRME were enrolled in this study. These patients underwent OCT to measure the fracture distance of the external limiting membrane (ELM), junction between the inner and outer segments (IS/OS), central foveal thickness (CFT), and edema layer.

View Article and Find Full Text PDF

Bulk chemicals such as ethylene glycol (EG) can be industrially synthesized from either ethylene or syngas, but the latter undergoes a bottleneck reaction and requires high hydrogen pressures. We show that fullerene (exemplified by C) can act as an electron buffer for a copper-silica catalyst (Cu/SiO). Hydrogenation of dimethyl oxalate over a C-Cu/SiO catalyst at ambient pressure and temperatures of 180° to 190°C had an EG yield of up to 98 ± 1%.

View Article and Find Full Text PDF

Objective: To develop nomograms that combine clinical characteristics, computed tomographic (CT) features and 18F-fluorodeoxyglucose PET (18F-FDG PET) metabolic parameters for individual prediction of epidermal growth factor receptor (EGFR) mutation status and exon 19 deletion mutation and exon 21 point mutation (21 L858R) subtypes in lung adenocarcinoma.

Methods: In total 124 lung adenocarcinoma patients who underwent EGFR mutation testing and whole-body 18F-FDG PET/CT were enrolled. Each patient's clinical characteristics (age, sex, smoking history, etc.

View Article and Find Full Text PDF

Background And Purpose: To investigate the efficacy and safety of intravenous thrombolysis (IVT) with alteplase in patients with central retinal artery occlusion (CRAO).

Methods: We searched the database of PubMed and EMBASE for potentially eligible studies that reported IVT in CRAO patients from their dates of inception to May 19, 2021. The rate and odds ratios (OR) of best-corrected visual acuity (BCVA) improvement, mean difference (MD) of BCVA with 95% confidence interval (CI) were pooled with random effects model.

View Article and Find Full Text PDF

Coinage metal nanoparticles with high dispersion can serve as highly efficient heterogeneous catalysts. However, owing to their low melting point, poor thermal stability remains a major obstacle towards their application under reaction conditions. It is a common practice to use porous inorganic templates such as mesoporous silica SBA-15 to disperse Ag nanoparticles (NPs) against aggregation but their stability is far from satisfactory.

View Article and Find Full Text PDF

Background And Purpose: Central retina imaging is important for early Parkinson's disease (PD) recognition. We aimed to investigate central retina changes using spectral domain-optical coherence tomography (SD-OCT) in PD patients.

Methods: We systematically searched PubMed and EMBASE to identify studies comparing the whole or individual layer thickness of central retina between PD patients and health controls using SD-OCT from inception to April 25, 2020.

View Article and Find Full Text PDF

In this work, surface modification of nano silver-loaded zirconium phosphate (6S-NP3) were obtained from simultaneous silanization of γ-methacryloxypropyltrimethoxysilane (MPS) and grafting reaction of methyl methacrylate (MMA), and then mixed with denture base resin (E-Denture) to prepare denture base composites using 3D printer printing. FT-IR spectra confirmed that surface silanization and grafting reaction had occurred and MPS and MMA were successfully anchored on the surface of 6S-NP3. XRD results demonstrated that surface modification had occurred on the surface of hexagonal lattice.

View Article and Find Full Text PDF

Objective: To explore the utility of dual-energy spectral computed tomography (CT) in the differential diagnosis of focal organizing pneumonia (FOP) and solitary bronchioloalveolar carcinoma (S-BAC).

Materials And Methods: The institutional review board approved this study and waived the requirement for informed consent. It is a retrospective study.

View Article and Find Full Text PDF