Antibacterial property expressed by a novel calcium phosphate glass.

We have developed a calcium phosphate glass (CPG) doped with Zn(2+) or F(-) or combined Zn(2+) and F(-) ions, which are naturally found in the human body and play a dual role in bone formation and antibacterial activity. Previously, we have demonstrated that this family of CPGs has superior osteoconductive and resorbable properties in vivo. This study aimed to investigate the antibacterial property of CPGs incorporating Zn(2+) and/or F(-) .

Improving the resistance to sliding contact damage of zirconia using elastic gradients.

Zirconia-based ceramics with high strength have been identified as a material of choice for sliding components in a variety of biomedical and engineering applications. Despite the high flexural strength, zirconia prostheses are still vulnerable to wear and surface damage. We hypothesize that such tribological damage may be substantially mitigated by an engineered grading of elastic modulus at the ceramic surface.