Publications by authors named "Lekkla A"

The prevalence of chronic Toxoplasma infections reported in the literature varies enormously. We hypothesize that one factor could be due to the different methods used in the evaluation of infections. Serological evidence of Toxoplasma infections in 450 pregnant women (PW) and 300 HIV-infected patients (HIV) were investigated by the Sabin-Feldman dye test and two other commercial ELISA kits (kit1 and kit2).

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The objective of this study was to investigate the epidemiology of toxoplasmosis in stray cats in Bangkok. Sera were collected during 2006 and examined by Sabin-Feldman dye test. Five hundred sixty-four male and 926 female cats in and around monasteries from 50 districts were collected.

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Toxoplasmosis caused by Toxoplasma gondii is a protozoan infection found worldwide. It usually produces non-specific symptoms, but in pregnant women and immunocompomised individuals, it may cause severe and fatal illness. Many serological studies have been done in various parts of the world, but information is lacking for Vietnam.

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Natural mineral water has long been used worldwide for bathing and health purposes. At present, Thailand is famous for health spas and natural hot springs among local people and tourists. Due to possible risks of exposure to harmful agents, we studied hazardous pollutants at 57 natural hot springs from 11 provinces in northern, central, eastern and southern Thailand.

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Thermo tolerant free-living ameba, Naegleria spp and Acanthamoeba spp contamination in natural hot springs in Thailand were carried out from 13 provinces. The temperature of hot springs water varied from 28 degrees-65 degrees C and pH from 6-8. We found that 38.

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Humans are thought to acquire Toxoplasma infection by three major routes: ingesting food and water contaminated with oocysts from cat excreta, consumption of under-cooked infected meat, and transplacental transfer. Congenital clinical toxoplasmosis in the newborn indicating definite transplacental transmission had been reported in Thailand, whilst studies concerning infection due to the other two routes were inconclusive. Since the way domestic cats live and eat and also the eating behavior of Thai people differ from those in the West, we conducted a sero-epidemiological study of T.

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Toxoplasma gondii IgG antibodies were determined in 200 kidney recipients by the Sabin-Felmand dye test. Twenty-two (11%) cases were positive for antibody detection. There was a statistically significant difference in the history of taking under-cooked meat, between the number of sero-positive cases and that of sero-negative subjects (63.

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The predictive value of commercial latex agglutination kit (Toxo-Screen DA, bioMerieux) was assessed for use as screening test for Toxoplasma IgG antibody. The sensivity and specificity were also compared with those of the reference standard Sabin-Feldman dye test. Five hundred serum samples were collected from 200 blood donors and 100 each from pregnant women, kidney recipients and HIV infected persons.

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Toxoplasmosis in an immunocompromised host was not documented in Thailand until 1992 when HIV/AIDS infection became pandemic. Patients with toxoplasmic encephalitis and cerebral abscess were recorded, particularly from the northern part of the country. However, data on the prevalence of the disease in HIV/AIDS patients is not yet available.

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One thousand two hundred pregnant women were examined for Toxoplasma gondii antibody with the objective of identifying the prevalence and risk factors of the disease. By using Sabin-Feldman Dye test, the prevalence of IgG to Toxoplasma gondii was 13.2%.

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