Publications by authors named "Lekaashree Rambabu"
Article Synopsis
- Papilledema is when the optic disc in the eye swells because there is too much pressure in the brain.
- Doctors can use special tools to look at the eye and see if papilledema is present, which helps them decide if more tests like MRIs or CT scans are needed.
- There is new research using artificial intelligence (AI) to help identify papilledema in the eyes, which could improve how doctors diagnose and treat this condition, especially where resources are limited.
Background: Natural disasters and infectious diseases result in widespread disruption to human health and livelihood. At the scale of a global pandemic, the co-occurrence of natural disasters is inevitable. However, the impact of natural disasters on the spread of COVID-19 has not been extensively evaluated through epidemiological modelling.
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- Phenthoate is a widely used organophosphorus pesticide that can cause serious health issues when ingested, with limited research available on its effects, prompting a study in Sri Lanka.
- In a study involving 292 patients who self-poisoned with phenthoate, 14.4% required intubation, with a notable case fatality rate of 6.5%, and deaths primarily occurred within the first 24 hours post-ingestion.
- The study noted a brief increase in cholinesterase enzyme activity in some patients treated with pralidoxime chloride, but this increase was not maintained over time, indicating challenges in effectively treating phenthoate poisoning.
Organophosphorus (OP) insecticide self-poisoning is a global problem, killing tens of thousands of people every year. Oxidative stress has been proposed to play a pathological role in OP poisoning, but whether it plays a direct toxic role is currently unclear. To determine whether there is consistent evidence of oxidative stress in patients with acute OP insecticide self-poisoning, and whether there are animal or human trial data that indicate that treatment of oxidative stress provides clinical benefit, which would suggest a direct toxic effect of oxidative stress.
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