Publications by authors named "Lejla Hadzikadic"
Hypothesis: Presenting the opinions of surgical residents about the appeal of trauma surgery as a specialty may influence current reform.
Design: Survey study.
Setting: Academic research.
A comprehensive review of prophylactic use of perioperative antibiotics in trauma from the 1970s to the present was performed. Evidence based guidelines were used to analyze the data from the past 32 years and define standards of care in the field. Recommendations and suggestions are provided to offer guidelines for prophylactic antibiotic use in trauma.
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- The immune response to cell-invading antigens relies heavily on the variability of major histocompatibility complex (HLA) class I molecules, which present different epitopes to T cells based on an individual's HLA genes.
- To effectively create vaccine strategies and monitor immune responses in diseases like cancer and viral infections, it's crucial to identify the specific HLA class I alleles and the epitopes they can present.
- This study introduces new PCR primers for amplifying HLA gene sequences, enabling gene typing and the creation of a recombinant HLA library, which can be used for generating soluble HLA molecules and discovering new epitopes.