Evaluation and Comparison of the Effects of Mature Silkworm () and Silkworm Pupae Extracts on Schwann Cell Proliferation and Axon Growth: An In Vitro Study.

Background: Silkworm products were first used by physicians more than 8500 years ago, in the early Neolithic period. In Persian medicine, silkworm extract has several uses for treating and preventing neurological, cardiac, and liver diseases. Mature silkworms () and their pupae contain a variety of growth factors and proteins that can be used in many repair processes, including nerve regeneration.