Publications by authors named "Leilani Lacson"

Article Synopsis
  • Tumor Treating Fields (TTFields) Therapy is an FDA-approved treatment for glioblastoma, but it isn't widely used despite evidence showing it can improve survival rates.
  • A study was conducted with 40 glioblastoma patients and 9 clinicians to understand their perspectives on the use of TTFields, focusing on reasons for acceptance or rejection of the therapy.
  • Results indicated that while patients were influenced by factors like device convenience and appearance, the efficacy of TTFields and clinician recommendations played a significant role in their decision-making process.
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Article Synopsis
  • * Interviews with 34 community organizations revealed that effective outreach strategies, resource coordination, and comprehensive training were critical needs to enhance their impact on communities experiencing poor COVID-19 outcomes.
  • * The findings emphasized the importance of using trusted messengers to reach populations with low vaccine confidence, and suggested that prioritizing resource replenishment and interorganizational collaboration is essential for sustainable COVID-19 prevention efforts.
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Aims: Heart failure (HF) is a common and morbid condition impacting multiple health domains. We previously reported the development of the PROMIS®-Plus-HF (PROMIS+HF) profile measure, including universal and HF-specific items. To facilitate use, we developed shorter, PROMIS+HF profiles intended for research and clinical use.

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Objective: To develop a symptom-focused index to evaluate representative symptoms, treatment side effects, and emotional and functional well-being of patients with carcinoid syndrome (CS).

Methods: The development of the Functional Assessment of Cancer Therapy-Carcinoid Syndrome Symptom Index (FACT-CSI) followed US Food and Drug Administration guidelines for the development of patient-reported outcome (PRO) measures and involved the following: (a) literature review; (b) interviews with 14 CS patients; (c) interviews with 9 clinicians; and (d) instrument development involving input from a range of PRO measure development and CS experts. The resulting draft instrument underwent cognitive interviews with 7 CS patients.

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Background: Although oxaliplatin is widely established as a standard treatment in colorectal cancer (CRC), oxaliplatin-induced neuropathy has emerged as a prominent dose-limiting side effect associated with quality of life decrements. Ongoing monitoring and management of neuropathy is important for CRC patient quality of life and adherence to treatment. Therefore, a validated self-reported measure of neuropathy would aid in the management and assessment of oxaliplatin-induced neuropathy in clinical practice and research.

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Purpose: Newly diagnosed breast cancer patients greatly overestimate their risk of developing contralateral breast cancer (CBC). Better understanding of patient conceptions of risk would facilitate doctor-patient communication and surgical decision making. In this mixed methods study, we prospectively examined breast cancer patients' perceived risk of future cancer and the reported factors that drove their risk perceptions.

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Objective: This study examined the content validity of the NCCN-FACT Ovarian Symptom Index-18 (NFOSI-18), an advanced ovarian cancer symptom index comprised of symptoms perceived as most important by clinical experts and women with advanced ovarian cancer.

Methods: Eighteen women with advanced ovarian cancer completed the NFOSI-18 and participated in cognitive interviews to assess: (a) the understandability of the NFOSI-18; and (b) the things patients have in mind when responding to the item, "I am bothered by side effects of treatment;" and (c) the interpretation patients place on items relating to fatigue and lack of energy. Interviews were recorded and transcribed for qualitative analysis.

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