A reliable QSPR model for predicting drug release rate from metal-organic frameworks: a simple and robust drug delivery approach.

During the drug release process, the drug is transferred from the starting point in the drug delivery system to the surface, and then to the release medium. Metal-organic frameworks (MOFs) potentially have unique features to be utilized as promising carriers for drug delivery, due to their suitable pore size, high surface area, and structural flexibility. The loading and release of various therapeutic drugs through the MOFs are effectively accomplished due to their tunable inorganic clusters and organic ligands.

Enhanced Photocatalytic CO Reduction by Novel Designed Porphyrin-Based MOFs: From Accurate QSPR Model to Experimental Exploration.

A reliable quantitative structure-property relationship (QSPR) model was established for predicting the evolution rate of CO photoreduction over porphyrin-based metal-organic frameworks (MOFs) as photocatalysts. The determination coefficient ( ) for both training and test sets was 0.999.