Publications by authors named "Leila Shayegan"
Background: Erosive pustular dermatosis of the scalp (EPDS) is an inflammatory cutaneous disorder typically affecting sun-damaged skin of mature individuals. Clinical features of EPDS include sterile pustules and chronic crusted erosions that can be hyperkeratotic and lead to scarring alopecia, atrophy, and telangiectasia. While the condition occurs on sun-damaged skin, a relationship with non-melanoma skin cancer (NMSC) has not been investigated.
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- Patients with epidermolysis bullosa (EB) have a risk of bacterial infections in their wounds and a subset are at risk for squamous cell carcinoma (SCC), leading to the need for careful wound management and analysis of bacterial cultures.
- A retrospective analysis of 739 wound cultures from 158 EB patients showed that Staphylococcus aureus and Pseudomonas aeruginosa were the most commonly found bacteria, with significant rates of antibiotic resistance observed.
- The findings emphasize the importance of monitoring bacterial resistance, as 47% of patients had methicillin-resistant S. aureus, reinforcing the need for effective antimicrobial strategies to prevent complications.
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- - This study describes a case of a rare primary immunodeficiency caused by mutations in the CARMIL2 gene, presenting in a child with symptoms similar to actinic prurigo.
- - The child's symptoms included skin issues triggered by sunlight (photodermatitis), a tendency to develop allergies, and frequent infections.
- - The case emphasizes the unique skin-related symptoms of this specific T-cell immunodeficiency and reviews other documented skin conditions associated with it in medical literature.
Background/objectives: Epidermolysis bullosa (EB) comprises a group of inherited skin blistering diseases. There is currently no cure, and management includes skin protection and prevention of infection. To date, there has been no systematic investigation of home skin care practices among EB patients on a multicenter scale.
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- Two pediatric patients with a history of chronic atopic dermatitis (AD) developed eruptive lentigines in areas where their AD had previously healed.
- These lentigines appeared at the sites of resolved AD, which is an unusual occurrence.
- This phenomenon has been rarely documented, especially in cases not involving the use of topical calcineurin inhibitors (TCIs).
We present a case of an infant with severe atopic dermatitis infected with Streptococcus pyogenes who presented with pustules, honey-colored crusts, and punched-out erosions with scalloped borders mimicking eczema herpeticum or eczema coxsackium. We draw attention to this case to highlight the similar clinical appearance between bacterial and viral infections in the setting of atopic dermatitis and the importance of a broad workup and coverage while awaiting results.
View Article and Find Full Text PDFShaving and other modes of epilation can cause undue anxiety, pain, or skin irritation in children. Here, we present hair trimming as a safe, painless, and cost-effective alternative for patients with unwanted hair which may be performed indefinitely or until the child is old enough to direct management. In select cases, removing unwanted hair using this technique may facilitate dermatologic surveillance.
View Article and Find Full Text PDFBackground: Working-memory impairment is a core cognitive dysfunction in people with schizophrenia and people at mental high risk. Recent imaging studies on working memory have suggested that abnormalities in prefrontal activation and in connectivity between the frontal and parietal regions could be neural underpinnings of the different stages of psychosis. However, it remains to be explored whether comparable alterations are present in people with subclinical levels of psychosis, as experienced by a small proportion of the general population who neither seek help nor show constraints in daily functioning.
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