Background: Stroke remains the leading cause of death and disability in the world. A new potential treatment for stroke is the granulocyte colony-stimulating factor (G-CSF), which exerts neuroprotective effects through multiple mechanisms. Memory impairment is the most common cognitive problem after a stroke.
View Article and Find Full Text PDFBackground: Endotracheal intubation is employed to create a safe airway in patients requiring mechanical ventilation. The relatively high prevalence rate of unplanned displacement of the endotracheal tube (ETT) can be associated with serious complications. This study was conducted to evaluate the effectiveness of a newly designed tube holder in Iran (Irafit), the Thomas ETT holder and the traditional method using adhesive tape.
View Article and Find Full Text PDFIntroduction: Global Cerebral Ischemia (GCI) causes neuronal damage with subsequent neurological and cognitive impairments. Curcumin has anti-inflammatory, antioxidant, and neuroprotective properties, which makes it a potential candidate for improving GCI-induced impairments. This study aimed to investigate the effects of curcumin on the neurological and memory deficits, as well as spatial neuronal distribution in the Cornu Ammonis 1 region after GCI in rats.
View Article and Find Full Text PDFStroke is a leading cause of mortality and disability; Memory impairment occurs frequently after stroke and the pattern of hippocampal CA1 pyramidal neurons has important role in the signal transmission and memory forming. G-CSF (granulocyte-colony stimulating factor) is a novel treatment that exhibits neuroprotective and anti-apoptotic in the central nervous system. The aim of the present study was to determine the effects of G-CSF on the neurobehavioral outcome and spatial pattern of CA1 pyramidal neurons after focal cerebral ischemia in animals.
View Article and Find Full Text PDFA plethora of investigations has substantiated a close relationship between cannabinoidergic and GABAergic systems in hippocampal CA1. The crucial role of these two systems in regulation of the addictive behaviors is well described. The aim of the current study was to investigate whether the CA1 GABAA receptors are involved in ACPA (a selective CB1 cannabinoid receptor agonist)-induced rewarding effects using the condition place preference (CPP) protocol.
View Article and Find Full Text PDFBackground: Poisoning is one of the most common medical presentations in a hospital. Hypoglycemic patients are at increased risk of toxicity. The purpose of this study was to compare capillary blood glucose and venous blood glucose measurements using glucometer against laboratory blood glucose in case of poisoned patients being in coma.
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