Publications by authors named "Leila J Saba"
Methods Mol Biol
December 2022
Article Synopsis
- LINE-1 (L1) retrotransposons create diverse ribonucleoproteins (RNPs) during their replication and the host's efforts to limit them, but their exact makeup is still not well understood.
- The composition of L1-associated macromolecules varies according to factors like the L1 life cycle stage, whether it’s dealt with productively or suppressed, and the specific cell type involved.
- This chapter presents techniques for identifying and analyzing the protein and RNA components of L1 macromolecules from tissues, using embryonal carcinoma cell lines (like N2102Ep) and colorectal cancer tissues as primary examples.
