INF2 mutations in Charcot-Marie-Tooth disease with glomerulopathy.

Background: Charcot-Marie-Tooth neuropathy has been reported to be associated with renal diseases, mostly focal segmental glomerulosclerosis (FSGS). However, the common mechanisms underlying the neuropathy and FSGS remain unknown. Mutations in INF2 were recently identified in patients with autosomal dominant FSGS.

[Effects of anxiety and depression on haemodialysis adequacy].

Unlabelled: Depression and anxiety are the most commonly encountered psychological problems in patients with end-stage renal disease, especially those on renal replacement therapy. We sought to assess the prevalence of anxiety and depressive symptoms in patients undergoing haemodialysis treatment and to establish the relationship between these psychological problems and criteria of haemodialysis adequacy.

Methods: We implemented a transversal study on 93 adult haemodialysis patients recruited from in Ibn-Sina Haemodialysis department in Rabat in April 2003.

[Renal graft rupture].

Spontaneous rupture of the renal graft is a serious early complication of renal transplantation, which can be responsible for loss of the graft. It usually follows an episode of acute rejection or acute tubular necrosis. It has a poor prognosis, as treatment consists of graft nephrectomy in the majority of cases.