L-Aspartic acid-functionalized magnetic nanoparticles: as a new magnetically reusable bifunctional acid-base catalysts for the synthesis of benzo[b]pyran and pyrano[3,2-c] chromene derivatives.

"Green chemistry" describes the development of new technologies that reduce or eliminate the need for hazardous compounds or the production of them. In order to accomplish this goal, we have developed a new magnetic recyclable biocatalyst in this study by successfully applying aspartic acid to magnetic nanoparticles. Aspartic acid's molecular makeup made it possible for it to stabilize on magnetic nanoparticles using a straightforward method.

Innovative synthesis of nano-magnetic bio-organocatalysts from red mud waste for green polyhydroquinoline derivatives synthesis.

The imperative of transforming waste materials into valuable nanomaterials via ecological recycling has emerged as a pivotal avenue for environmental stewardship. This research contributes to the "greening" of global chemical processes by introducing a magnetic biocatalyst derived from red mud waste. Emphasizing the use of glutamic acid as the second most effective step in obtaining a green catalyst is a key focus of this work.

A novel heterogeneous biocatalyst based on graphene oxide for synthesis of pyran derivatives.

Graphene oxide modified with tryptophan (GO-Trp) has been introduced as a new heterogeneous acid-base biocatalyst for synthesis of some pyran derivatives. GO was prepared according to the Hummer's method and tryptophan as a low-cost green amino acid is covalently bonded to the surface of GO without any organic or toxic reagents in a green way. The new catalyst was characterized by different spectroscopic methods such as Fourier transform infrared, X-ray diffraction (XRD), etc.

Graphene oxide immobilized 2-morpholinoethanamine as a versatile acid-base catalyst for synthesis of some heterocyclic compounds and molecular docking study.

In this study, a new heterogeneous catalyst was synthesized based on graphene oxide (GO) as a natural material. On the surface of nanosheet graphene oxide, 2-Morpholinoethanamine was immobilized using a non-toxic, green, and simple method. This resulted in the preparation of a bifunctional acid-base nanocatalyst.

A novel heterogeneous acid-base nano-catalyst designed based on graphene oxide for synthesis of spiro-indoline-pyranochromene derivatives.

Nano graphene oxide/3-aminopyridine has been introduced as a new, efficient and robust heterogeneous organic catalyst for synthesis of spiro-indoline-pyranochromene derivatives. Nano graphene oxide/3-aminopyridine was provided in an easy and green way from GO. Firstly, graphene oxide (GO) was synthesized and then 3-aminopyridine was immobilized with covalent bonds on its surface as a nitrogenous organic compound, in this step we didn't use any organic or toxic substance.

Fabrication of a label-free electrochemical aptasensor to detect cytochrome c in the early stage of cell apoptosis.

A label-free direct electrochemical aptasensor is presented for the identification of cytochrome c (Cyt c) at the nM concentration level. Carbon nanofibers (CNF), as a highly conductive material, were used to modify a glassy carbon electrode (GCE) and thus increase its conductivity. Moreover, to enhance the immobilization of aptamers (Apt) on the electrode surface, graphene oxide functionalized with aspartic acid (GOAsp) was added to the surface.

Efficient synthesis of 1,3-naphtoxazine derivatives using reusable magnetic catalyst (GO-FeO-Ti): anticonvulsant evaluation and computational studies.

A series of 2-aryl/alkyl-2,3-dihydro-1H-naphtho[1,2-e][1,3]oxazines (S-S) were synthesized with an eco-friendly and recoverable nanocatalyst (GO-FeO-Ti) as an efficient magnetic composite. The new nanocatalyst was characterized by FT-IR, XRD and, EDS analysis. A conformable procedure, easy to work up and having a short reaction time with high yields are some advantages of this method.

Anticonvulsant activity, molecular modeling and synthesis of spirooxindole-4H-pyran derivatives using a novel reusable organocatalyst.

Fifteen derivatives of spirooxindole-4H-pyran (A-A) were subjected to evaluate through intravenous infusion of pentylenetetrazole (PTZ)-induced epilepsy mouse models. Four doses of the compounds (20, 40, 60 and 80 mg/kg) were tested in comparison with diazepam as positive control. The resulted revealed that compounds A and A were the most active compounds and indicated significant anticonvulsant activity in the PTZ test.