Background: Drug hypersensitivity reactions (DHRs) have a significant impact on both, patient and their treating physicians; it is considered a public health concern. The history of allergy to drugs, limits therapeutic options and will lead to the use of more expensive and potentially less effective options. Drug desensitization (DD) is considered as a procedure with a positive impact on the prognosis of the patient's disease.
View Article and Find Full Text PDFBackground: This study investigates the association between inflammatory myopathies (IM), and their correlation with cancer. There are several potential causes behind the association of cancer and inflammatory myopathies. The positivity of specific antibodies for myositis plays a significant role.
View Article and Find Full Text PDFHistoplasmosis presents a substantial clinical challenge globally, with a particular prevalence in South America, especially among patients with concurrent Human Immunodeficiency Virus (HIV) infection. Despite itraconazole's established efficacy, investigating alternative therapeutic approaches remains imperative. This is the largest study in our region to date, assessing the effectiveness of the less explored posaconazole treatment.
View Article and Find Full Text PDFBMC Infect Dis
September 2023
Background: Salmonellosis is a major cause of morbidity and mortality and one of the most frequent etiologies of diarrhea in the world. Mortality due to Salmonellosis in Latin America still poorly understood, and there is a lack of studies that evaluate resistance and clinical manifestations. The aims of this study were to characterize patients infected with Salmonella spp.
View Article and Find Full Text PDFObjectives: To evaluate how the food systems in areas close to sugarcane monocrops influence the prevalence of food insecurity (FI) among three ethnic communities in the upper Cauca River basin of Colombia.
Methods: We developed a mixed methodology study at three rural zones located in the departments of Cauca and Valle del Cauca, Colombia, using a household survey to establish the level of FI, and semi-structured interviews with key community actors.
Results: These three ethnic communities have a high prevalence of FI (> 70%) that was found to be associated with economic income, social security, gender, the presence of minors in the home, refrigerator in operation and ownership of the land.