Publications by authors named "Leiderman S"
Article Synopsis
- Excessive androgen levels in postmenopausal women are often due to hormonal imbalances, primarily a rapid decline in estrogen and a slower decrease in androgens, alongside lower levels of sex hormone-binding globulin.
- *Hyperandrogenism poses risks such as increased cardiovascular issues, gynecological cancers, and negative effects on women's emotional health, making proper evaluation essential for treatment.
- *Common symptoms women may experience include facial hair growth and hair loss; sudden onset or severe symptoms warrant further investigation for potential tumors, with diagnosis assisted by medical history, testosterone level testing, and imaging studies.
Estrogenic status influences nitric oxide-regulated TNF-alpha release from human peripheral blood monocytes.
Exp Clin Endocrinol Diabetes
December 2001
Cytokines and nitric oxide (NO) have been implicated in bone loss caused by estrogen deficiency. Here we evaluated the effect of nitric oxide synthase (NOS) inhibitors on the bone particle resorbing activity and TNF-alpha release of cultured peripheral blood monocytes (PBM) obtained from 10 premenopausal (PreM) and 10 postmenopausal (PostM) women. Gonadal status (menopause < 3 yr) was assessed by FSH and estradiol.
View Article and Find Full Text PDFEstrogenic activities of estradiol enantate and ethinylestradiol compared at a clinical level.
Arzneimittelforschung
November 1986
Healthy menopausic women accepted to receive two consecutive estrogenic treatments: 1. ethinylestradiol 0.030 mg/d p.
View Article and Find Full Text PDFThe effect of oral contraceptives on the gonadotropin response to LHRH.
Obstet Gynecol
November 1978
This study was designed to assess the effect of long-term treatment with three combined oral contraceptives (OC) on the gonadotropin response to LHRH. The release of LH and FSH after a single 50-microgram dose of LHRH was studied from Days 11 to 14 of treatment and Days 2 and 3 after discontinuation of the treatment. The responses were compared with controls during the luteal phase (Days 16 to 19) of the menstrual cycle.
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