Publications by authors named "Lei-Ming Xia"

Background: Obstetric hemorrhage is a major cause of maternal death during cesarean delivery. The objective of this retrospective observational study was to evaluate the efficacy and safety of intra-operative cell salvage (IOCS) in cesarean section.

Methods: We included a total of 361 patients diagnosed with central placenta previa who underwent cesarean section from May 2016 to December 2018.

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Article Synopsis
  • - miR-100-3p is implicated in the regulation of gastric cancer (GC) progression, exhibiting lower expression levels in GC cell lines and cancerous tissues compared to normal cells.
  • - The study demonstrates that loss of miR-100-3p enhances tumor growth and increases the expression of bone morphogenetic protein receptor 2 (BMPR2), while its over-expression has the opposite effect, suggesting a complex interaction between these factors.
  • - Findings highlight that miR-100-3p may function as a tumor suppressor by down-regulating BMPR2, thereby inhibiting the ERK/AKT pathway and activating pro-apoptotic signals, which could provide new opportunities for GC treatment strategies.
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