Publications by authors named "Lei S Li"

Article Synopsis
  • Photoacoustic computed tomography (PACT) is a rapidly growing biomedical imaging technique that combines optical and acoustic methods for improved imaging.
  • The review highlights key challenges in PACT, such as limited view, anisotropy resolution, and acoustic heterogeneity, while discussing potential solutions.
  • Advances from both industry and academia, including deep learning methods, are being explored to enhance PACT performance and address its limitations.
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Significance: Wavefront shaping (WFS) can compensate for distortions by optimizing the wavefront of the input light or reversing the transmission matrix of the media. It is a promising field of research. A thorough understanding of principles and developments of WFS is important for optical research.

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A three-dimensional (3D) holographic display (3DHD) can preserve all the volumetric information about an object. However, the poor fidelity of 3DHD constrains its applications. Here, we present an ultrahigh-fidelity 3D holographic display that uses scattering for homogenization of angular spectrum.

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Significance: Optical imaging of responses in fluorescently labeled neurons has progressed significantly in recent years. However, there is still a need to monitor neural activities at divergent spatial scales and at depths beyond the optical diffusion limit.

Aim: To meet these needs, we aim to develop multiscale photoacoustic tomography (PAT) to image neural activities across spatial scales with a genetically encoded calcium indicator GCaMP.

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To study the predictive value of biopsy lesions in IgA nephropathy in a range of patient ages we retrospectively analyzed the cohort that was used to derive a new classification system for IgA nephropathy. A total of 206 adults and 59 children with proteinuria over 0.5 g/24 h/1.

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Unlabelled: Emodin ameliorates glucose-induced matrix synthesis in human peritoneal mesothelial cells. Prolonged exposure of human peritoneal mesothelial cells (HPMC) to high glucose concentrations in peritoneal dialysate is the principal factor leading to matrix accumulation and thickening of the peritoneal membrane, accompanied by progressive deterioration of transport functions. These changes are mediated in part through protein kinase C (PKC) activation and the induction of transforming growth factor-beta 1 (TGF-beta 1).

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