Predictive Factors for New-Onset Left Bundle Branch Block in Patients with Left Ventricular Systolic Dysfunction and Its Prognostic Value.

It remains unclear whether elevated ventricular wall pressure and left ventricular enlargement in patients with left ventricular systolic dysfunction (LVSD) can lead to left bundle branch block (LBBB). In this study, 801 consecutive hospitalized patients with a left ventricular ejection fraction of < 50% were enrolled. The primary outcome was the occurrence of new-onset LBBB or heart failure-related hospitalization, all-cause mortality, ventricular tachycardia, or implantation of an implantable cardioverter-defibrillator (ICD) /cardiac resynchronization therapy (CRT).

Epidemiology and prognostic nomogram for locally advanced gastric signet ring cell carcinoma: A population-based study.

Background: Gastric signet ring cell carcinoma (GSRC) represents a specific subtype of gastric cancer renowned for its contentious epidemiological features, treatment principles, and prognostic factors.

Aim: To investigate the epidemiology of GSRC and establish an improved model for predicting the prognosis of patients with locally advanced GSRC (LAGSRC) after surgery.

Methods: The annual rates of GSRC incidence and mortality, covering the years 1975 to 2019, were extracted from the Surveillance, Epidemiology, and End Results (SEER) database to explore the temporal trends in both disease incidence and mortality rates using Joinpoint software.

Study on Seepage Characteristics of Grouting Slurry for Water-Absorbing Mudstone with Rough Fissure.

Based on the computed tomography scanning, which abbreviation is CT scanning, and fractal theory, geometric parameters of mudstone fissures are obtained. The physical model of a single fissured channel is obtained in combination with Barton standard curves and 3D printing technology, and similar materials of mudstone are developed based on the water absorption of natural mudstone to prepare single fissured water-absorbing grouting test blocks with different roughness levels for the grouting simulation testing. By analyzing the viscosity change characteristics of grouting slurry before and after grouting, the seepage characteristics of the grouting slurry in the rough fissures of the water-absorbing mudstone are revealed.

Global trends of targeted therapy for hepatocellular carcinoma: A bibliometric and visualized study from 2008 to 2022.

Background: Hepatocellular carcinoma (HCC) is an exceedingly prevalent malignancy with an exceptionally poor prognosis. Targeted therapy is an effective treatment option for patients with advanced HCC. However, there have been no bibliometric analyses of targeted therapies for HCC.

Case Report: Adult degenerative scoliosis in two patients treated with percutaneous spinal endoscopic-assisted lumbar interbody fusion and percutaneous pedicle screw fixation.

Adult degenerative scoliosis (ADS) is a serious disease that often affects middle-aged and elderly people. ADS does not only cause sagittal and coronal deformity of the lumbar spine but also causes severe back and leg pain secondary to the compression of the neural structures. Open surgery remains the main method for correcting the occurring deformity and decompression of the neural structures; however, its benefit is limited in cases of large trauma.

Association between complete right bundle branch block and atrial fibrillation development.

Background: Complete right bundle branch block (CRBBB) is an important predictor of atrial fibrillation (AF) recurrence after pulmonary vein isolation. However, the association between CRBBB and AF development remains unclear.

Methods: We performed a retrospective study of 2639 patients (male, n = 1549; female, n = 1090; mean age, 58 ± 13 years).

Effect of catheter ablation on clinical outcomes in patients with atrial fibrillation and significant functional mitral regurgitation.

Background: In patients with atrial fibrillation (AF) and functional mitral regurgitation (MR), catheter ablation reduces the severity of MR and improves cardiac remodeling. However, its effects on prognosis are uncertain.

Methods: This retrospective study included 151 consecutive patients with AF and functional MR, 82 (54.

Manipulative experiments networks on response and adaptation of terrestrial ecosystems to environmental changes: Building the research methods and technology system.

The feedback relationship between organisms or ecosystems and environment has been a key issue in ecological research. Manipulative experiments with changing biological or environmental factors and large-scale field experiment networks were regarded as effective approaches to understand and accurately quantify the process and mechanisms underlying ecosystem response and adaptation to environmental changes. In recent years, a few networks have been developed, including large-scale networks of field physics simulation experiment (.

[A coordinated three-dimensional network for observing large-scale terrestrial ecosystem status changes and the consequences on resources and environment].

Co-driven by environmental change and human activity, global ecosystem has been experiencing rapid changes, with cascading effects on resources and environment. The changes of ecosystem status and its spatiotemporal evolution drivers, and the related resource and environmental effects have been recognized as the long standing topics of large-scale terrestrial ecosystem science. The coordinated observation networks distributed across different continents and the globe provide the valuable tools for observing and evaluating ecosystem state change, for revealing and elaborating mechanisms underlying ecosystem response, for cognizing and understanding ecosystem evolution, and for predicting and early-warning of ecosystem change.

PU.1 inhibition attenuates atrial fibrosis and atrial fibrillation vulnerability induced by angiotensin-II by reducing TGF-β1/Smads pathway activation.

Fibrosis serves a critical role in driving atrial remodelling-mediated atrial fibrillation (AF). Abnormal levels of the transcription factor PU.1, a key regulator of fibrosis, are associated with cardiac injury and dysfunction following acute viral myocarditis.

[Technical approach and strategic plan for large-scale ecological and environmental gover-nance and national ecological security pattern construction.].

Terrestrial ecosystems are the core components of the biosphere, supporting human life, production and social and economic activities. With the development of human civilization and the progress of science and technology, the continued expanding resources utilization in terms of scale and intensity has caused environmental problems, including global climate change, biodiversity loss, environmental pollution, resource depletion and ecosystem degradation, which threaten the sustainable development of our society. The public expects ecological research providing scientific theories and systematic solutions for the utilization and protection of ecosystems at the continental and global scale, and the maintenance of sustainable development of human society as well.

Escin ameliorates the impairments of neurological function and blood brain barrier by inhibiting systemic inflammation in intracerebral hemorrhagic mice.

This study aims to investigate whether escin ameliorates the impairments of neurological function by ameliorating systemic inflammation instead of targeting the brain directly in intracerebral hemorrhage (ICH) mice. It showed that escin did not cross the blood brain barrier (BBB). Compared with the ICH group, the Garcia test scores in the escin groups were significantly increased.

Effect of pulmonary vein isolation on atrial fibrillation recurrence after accessory pathway ablation in patients with Wolff-Parkinson-White syndrome.

Background: Although successful ablation of the accessory pathway (AP) eliminates atrial fibrillation (AF) in some of patients with Wolff-Parkinson-White (WPW) syndrome and paroxysmal AF, in other patients it can recur.

Hypothesis: Whether adding pulmonary vein isolation (PVI) after successful AP ablation effectively prevents AF recurrence in patients with WPW syndrome is unknown.

Methods: We retrospectively studied 160 patients (102 men, 58 women; mean age, 46 ± 14 years) with WPW syndrome and paroxysmal AF who underwent AP ablation, namely 103 (64.

Comparative study of curative effect of spinal endoscopic surgery and anterior cervical decompression for cervical spondylotic myelopathy.

Background: The aim of this study was to compare the clinical efficacy of endoscopic cervical spinal surgery with anterior cervical decompression and fusion (ACDF) in the treatment of cervical spondylotic myelopathy (CSM).

Methods: A total of forty-six CSM patients who were admitted to the Medical School of Chinese PLA and treated with endoscopic spine surgery or ACDF from January 2015 to June 2017 were collected. The patients were divided into the spinal endoscopy group and the ACDF group, according to the operation methods.

Percutaneous endoscopic decompression for calcified thoracic disc herniation using a novel T rigid bendable burr.

Background: The basic endoscopic instruments are not suitable for removing calcified or hard discs in patients with thoracic disc herniations (TDH). We describe a percutaneous endoscopic technique for the treatment of calcified TDH using an endoscopic drill system with a T rigid bendable burr.

Methods: Eleven patients (8 males, mean age 42.

Atmospheric deposition of polycyclic aromatic compounds and associated sources in an urban and a rural area of Chongqing, China.

Monthly bulk (dry + wet) deposition samples were collected at an urban and a rural site in Chongqing, southwestern China during May 2014 to April 2015 for analyzing the contents of parent polycyclic aromatic hydrocarbons (PPAHs) and three types of substituted PAHs (SPAHs) including oxygenated PAHs (OPAHs), nitrated PAHs (NPAHs) and methyl PAHs (MPAHs). Annual average (±standard deviation) deposition fluxes of ΣPPAHs, ΣOPAHs, and ΣMPAHs were 536 ± 216; 221 ± 118, and 131 ± 41.9 ng/m/d, respectively, in the urban area, and 347 ± 185, 160 ± 112, and 85.

Assessment of the knowledge, attitude and practices about Human Papilloma Virus vaccine among the nurses working in a tertiary hospital in China: A cross-sectional descriptive study.

Objective: To assess the knowledge about human papilloma virus infection and vaccine, to ascertain the attitude and practices about the vaccine, and to ascertain the determinants preventing people from getting themselves vaccinated.

Methods: The cross-sectional descriptive study was conducted from June to August 2015 in Henan Provincial People's Hospital, Henan, China, and comprised all the nursing staff including nursing students. A piloted semi-structured questionnaire was used for collecting data.

Highly time-resolved characterization of water-soluble inorganic ions in PM in a humid and acidic mega city in Sichuan Basin, China.

To investigate the characteristics of water-soluble inorganic ions (WSIIs) in Chongqing, a well-known foggy and acid region in southwestern China, hourly real-time concentrations of five cations (Na, K, NH, Ca, and Mg) and six anions (F, Cl, NO, NO, PO, and SO) in PM during winter (from Dec. 18, 2015 to Mar. 20, 2016) in Chongqing were collected by applying In-situ Gas and Aerosol Compositions Monitor.

Paeonol protects endotoxin-induced acute kidney injury: potential mechanism of inhibiting TLR4-NF-κB signal pathway.

Study Design And Methods: In order to determine the therapeutic effect and mechanism of paeonol on acute kidney injury induced by endotoxin, an acute kidney injury model was established by intraperitoneal administration of lipopolysaccharide in mice in vivo and on LPS-induced dendritic cells in vitro. Renal tissues were used for histologic examination. Concentrations of blood urea nitrogen and serum creatinine were detected, inflammatory cytokines were determined by ELISA.

[Simulation and validation of diffuse radiation in Qianyanzhou area, Jiangxi, China].

Accurate estimation of diffuse radiation is of great significance for evaluating its effect on terrestrial ecosystem carbon exchange. Based on the observed diffuse radiation data in the meteorological observation field in mid-subtropical Qianyanzhou, Jiangxi, China from March 1, 2012 to February 28, 2013, the simulated results of five widely used diffuse radiation decomposition models (Reindl-1, Reindl-2, Reindl-3, Boland, BRL) were validated. The results indicated that, on the 30 min scale, all of the five models could well simulate the diffuse radiation of this area overall.

[Comparative observation of diffuse radiation in Qianyanzhou during the spring of 2012].

Global radiation and diffuse radiation were measured from March to June of 2012 in Qianyanzhou Experimental Station of Red Soil and Hilly Land, Chinese Academy of Sciences by ising three types of pyranometers, including CMP11 attached with a shadow ring, SPN1 and RSR3, which were placed in parallel. The observations showed that both global radiation and diffuse radiation measured by these pyranometers had a good linear correlation. The global radiation measured by SPN1 and RSR3 was respectively 3.

[Characteristics of carbon storage of Inner Mongolia forests: a review].

Forests in Inner Mongolia account for an important part of the forests in China in terms of their large area and high living standing volume. This study reported carbon storage, carbon density, carbon sequestration rate and carbon sequestration potential of forest ecosystems in Inner Mongolia using the biomass carbon data from the related literature. Through analyzing the data of forest inventory and the generalized allometric equations between volume and biomass, previous studies had reported that biomass carbon storage of the forests in Inner Mongolia was about 920 Tg C, which was 12 percent of the national forest carbon storage, the annual average growth rate was about 1.