Publications by authors named "Lei Jun-Qiang"
Article Synopsis
- * The research included 11 studies with 1,702 participants and identified 13 CMR parameters linked to AR prognosis, focusing specifically on four key metrics: aortic regurgitation fraction (ARF), aortic regurgitation volume (ARV), and left ventricular volumes (LVEDV and LVESV).
- * Findings suggest that ARF, LVEDV, and LVESV are significant indicators of prognosis in AR patients, making it crucial
Article Synopsis
- * Surgical options are currently the only curative treatments, but most patients relapse within five years, with microvascular invasion (MVI) being a crucial factor linked to survival outcomes.
- * Accurate preoperative prediction of MVI is essential for better treatment decisions, yet there are no standard criteria for diagnosing MVI, leading to ongoing research in imaging techniques to improve accuracy and outcomes.
Article Synopsis
- This study explored using advanced dual-layer spectral CT imaging to predict microvascular invasion (MVI) in patients with hepatocellular carcinoma (HCC).
- It analyzed data from 50 HCC patients, focusing on differences in clinical and radiological factors between those with MVI and those without, finding several significant predictors.
- The results indicated that normalized iodine concentration (NIC) at 40 keV images was particularly effective in distinguishing between the two groups, providing valuable information for clinical decision-making and prognosis.
Article Synopsis
- In patients with chronic aortic regurgitation, traditional measures of heart function like left ventricular ejection fraction can overlook early dysfunction, making global longitudinal strain (GLS) and tissue motion annular displacement (TMAD) useful for assessment.
- This study compared the effectiveness of TMAD and GLS in evaluating left ventricular function, involving 96 patients with severe aortic regurgitation and 45 healthy individuals, using advanced imaging techniques.
- Results showed that TMAD provided more consistent and quicker assessments compared to GLS, with the global Midpt% parameter being highly correlated with GLS and LVEF, suggesting it could be a reliable alternative in clinical settings.
Article Synopsis
- * The study utilized density functional theory (DFT) to analyze molecular interactions, UV-Vis spectra, bond lengths, and other properties of these dyes.
- * Differences in luminescence and energy gaps between Cy5.5 and Cy7.5 were linked to the length of the conjugated chains between their aromatic rings, providing insights for future dye modifications and applications.
Article Synopsis
- The study aimed to develop a non-invasive tool using radiomics and ultrasound features from automated breast volume scanning (ABVS) to evaluate axillary lymph node metastasis (ALNM) in early invasive breast cancer patients.
- The researchers analyzed ABVS images from two different centers, creating a model that combines significant factors to predict ALNM risk through a nomogram.
- The final model demonstrated moderate predictive ability, offering a better evaluation of both positive and micrometastatic ALNs, which aids clinicians in making informed decisions about diagnosis and treatment.
Objectives: Accurate preoperative diagnosis of small cell neuroendocrine cancer of the cervix (SCNECC) is crucial for establishing the best treatment plan. This study aimed to develop an improved, non-invasive method for the preoperative diagnosis of SCNECC by integrating clinical, MR morphological, and apparent diffusion coefficient (ADC) information.
Methods: A total of 105 pathologically confirmed cervical cancer patients (35 SCNECC, 70 non-SCNECC) from multiple centres with complete clinical and MR records were included.
Rationale: Presence of synchronous double hepatocelluar carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC) (sdpHCC-ICC) located separately within a single liver is extremely rare. The purpose of this study is to investigate the clinical, imaging, pathological characteristics, and prognosis of patients with sdpHCC-ICC, in order to enhance our understanding of the disease and improve diagnostic and therapeutic effect.
Patient Concerns: A 49-year-old, female with the diagnosis of hepatitis B virus with obvious liver cirrhosis, was admitted to our hospital.
Objective: To explore the efficacy of the quantitative parameter histogram analysis of intravoxel incoherent motion (IVIM) for different molecular prognostic factors of breast cancer.
Materials And Methods: A total of 72 patients with breast cancer who were confirmed by surgical pathology and underwent preoperative magnetic resonance imaging (MRI) were analyzed retrospectively. A region of interest (ROI) was drawn in each slice of the IVIM images.
The aim of the study was to assess the potential role of preoperative gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid (Gd-EOB-DTPA) dynamic enhanced MR imaging for diagnosing microvascular invasion (MVI) and pathological grade of hepatocellular carcinoma (HCC).A total of 113 consecutive HCC patients confirmed by histopathology underwent preoperative Gd-EOB-DTPA dynamic enhanced MRI were included. Signal intensity (SI) of peritumoral, normal liver tissue and tumor parenchyma during arterial phase and hepatobiliary phase (HBP) were analyzed.
View Article and Find Full Text PDFBackground: To investigate the value of 18F-fluorodeoxyglucose positron emission tomography/magnetic resonance imaging (18F-FDG PET/MRI) in diagnosing local tumor invasion (T stage), evaluating regional lymph node involvement (N stage), and detecting distant metastasis (M stage) in breast cancer patients.
Methods: A comprehensive computer search and manual search were performed to select any potentially eligible studies that evaluated the diagnostic efficacy of 18F-FDG PET/MRI in the tumor-node-metastasis (TNM) staging of breast cancer. Data from the included studies were extracted to calculate the pooled sensitivity, specificity, and area under the curve (AUC) to evaluate the value of 18F-FDG PET/MRI in TNM staging.
Rationale And Objectives: To assess differences of dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) parameters at different postcontrast time points (TPs), and to explore the predictive value of DCE-MRI parameters for axillary lymph node (ALN) metastasis of breast cancer.
Materials And Methods: A total of 107 breast cancer patients were included retrospectively, and 50 phases were collected on DCE-MRI for each patient. DCE-MRI parameters Ktrans, Kep, Ve, TTP, Peak, Washin, Washout, and AUC were extracted from the images at 67.
The purpose of this case report is to describe the multimodal cardiac magnetic resonance (CMR) imaging features of an invasive thymoma extending into the superior vena cava and right atrium. This unusual case indicates that multimodal CMR can not only reveal the morphological features of thymoma but also enable the identification of histological types, which provides a reasonable surgical plan in the perioperative management. < Invasive thymoma can invade the superior vena cava and extend into the right atrium.
View Article and Find Full Text PDFObjective: To evaluate the diagnostic performance of magnetic resonance hysterosalpingography for fallopian tubal occlusion in the context of female infertility when compared to the diagnostic performance of conditional X-ray hysterosalpingography.
Methods: PubMed, EMBASE, Web of Science, EBSCO, Cochrane Library database, Scopus were searched for studies in which magnetic resonance hysterosalpingography and X-ray hysterosalpingography were used as diagnostic tools for tubal occlusion assessment; databases were searched through April 2020. Two researchers conducted study inclusion assessment, data extraction, a systematic review, and pooled meta-analysis independently.
Objective: To observe the effect of acupuncture plus hyperbaric oxygen (HBO) on cerebral blood perfusion in patients with delayed encephalopathy after carbon monoxide poisoning (DEACMP).
Methods: Twenty-eight patients with DEACMP were randomly divided into acupuncture group (=14 cases) and control group (=14 cases). Patients of the acupuncture group were treated by using "Xingnao Kaiqiao" needling technique (specific set of acupuncture points as Yintang ［EX-HN3］, Shangxing ［GV23］, Baihui ［GV20］, Sishenchong ［EX-HN1］, Fengchi ［GB20］, Taichong ［LR3］, etc.
Rationale And Objectives: To investigate the value of gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid (Gd-EOB-DTPA)-enhanced magnetic resonance imaging (MRI) and diffusion-weighted imaging (DWI) in diagnosing residual hepatocellular carcinoma (HCC) after drug-eluting bead transarterial chemoembolization (DEB-TACE).
Materials And Methods: Sixty-two patients (50 men, 12 women; mean age, 56.8 ± 1.
Background: Cardiac masses are rare, but lead to high risk of stroke and death. Because of the different treatment methods, it is significant for clinicians to differentiate the nature of masses. Cardiac magnetic resonance (CMR) imaging has high intrinsic soft-tissue contrast and high spatial and temporal resolution and can provide evidence for differential diagnosis of cardiac masses.
View Article and Find Full Text PDFBackground: Accurate and early diagnosis of residual tumors or intrahepatic recurrences after TACE is critically needed for determining the success of treatments and for guiding subsequent therapeutic planning. This meta-analysis was performed to assess the efficacy of diffusion weighted imaging (DWI) with the quantitative apparent diffusion coefficient (ADC) value in diagnosing residual or recurrent hepatocellular carcinoma after transarterial chemoembolization (TACE).
Materials And Methods: A comprehensive literature search of PubMed, Embase, Web of Science, Scopus and the Cochrane Library database, from inception to July 2019, was conducted to select original studies on diagnosing residual or recurrent HCCs after TACE using DWI sequence with its ADC value.
Objective: To evaluate the diagnostic accuracy of transthoracic echocardiography (TTE) in patients with pulmonary hypertension (PH).
Design: Systematic review and meta-analysis.
Data Sources And Eligibility Criteria: Embase, Cochrane Library for clinical trials, PubMed and Web of Science were used to search studies from inception to 19 June, 2019.
Background: Conventional diffusion-weighted imaging is limited in the quantitative evaluation of liver fibrosis, and whole-liver apparent diffusion coefficient (ADC) histogram analysis might contribute to the diagnosis and staging of liver fibrosis.
Purpose: To explore the value of whole-liver ADC histogram parameters in the diagnosis and staging of liver fibrosis.
Study Type: Retrospective.
Objective: Quantitative assessment of white blood flow in semi-oval center of patients with delayed neuropathological sequelae (DNS) after carbon monoxide poisoning treated with acupuncture combined with hyperbaric oxygen (HBO) based on magnetic resonance multi-inversion time arterial spin labeling imaging (mTI-ASL), and to evaluate its efficacy indirectly.
Methods: Twenty-six patients with clinically diagnosed DNS were randomly divided into an observation group (13 cases) and a control group (13 cases). The conventional therapy combined with HBO were given in the control group.
Purpose: The study evaluated the relationship between the histological grade of hepatocellular carcinoma (HCC) and the histogram-derived parameters of apparent diffusion coefficient (ADC) obtained from the whole-lesion assessment of diffusion-weighted magnetic resonance (MR) imaging in the liver.
Methods: A total of 51 patients were included. The parameters were correlated with the Edmondson-Steiner grades by using the Spearman correlation coefficient (ρ).
Acupuncture is widely used in the treatment of ischemic diseases of the central nervous system in different clinical stages and has achieved a good clinical effect. The current research showed that acupuncture can improve cerebral blood flow perfusion via increasing blood flow volume, blood flow velocity, the levels of vasomotor substances and reduction of blood viscosity and erythrocyte aggregation index. In recent years, many studies focused on the pathophysiological mechanism of acupuncture in improving cerebral ischemia via triggering the cholinergic vasodilatation, up-regulation of expression of vascular-related proteins and genes，attenuation of inflammatory reaction, etc.
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