A pair of long intergenic non-coding RNA LINC00887 variants act antagonistically to control Carbonic Anhydrase IX transcription upon hypoxia in tongue squamous carcinoma progression.

Background: Long noncoding RNAs (lncRNAs) are important regulators in tumor progression. However, their biological functions and underlying mechanisms in hypoxia adaptation remain largely unclear.

Results: Here, we established a correlation between a Chr3q29-derived lncRNA gene and tongue squamous carcinoma (TSCC) by genome-wide analyses.

Decoding the role of long noncoding RNAs in the healthy aging of centenarians.

Aging is the largest risk factor of major human diseases. Long noncoding RNAs (lncRNAs) as the key regulatory elements have shown a strong impact on multiple biological processes as well as human disease mechanisms. However, the roles of lncRNAs in aging/healthy aging processes remain largely unknown.

Facial Emotion Perceptual Tendency in Violent and Non-violent Offenders.

All three authors share equal authorship in this paper.Emotion perception has a vital influence on social interaction. Previous studies discussed mainly the relationship between facial emotion perception and aggressive behavior from the perspective of hostile attributional bias and the impaired violence inhibition mechanism.

Insights into long noncoding RNAs of naked mole rat () and their potential association with cancer resistance.

Background: Long noncoding RNAs (lncRNAs) are a class of ubiquitous noncoding RNAs and have been found to act as tumor suppressors or oncogenes, which dramatically altered our understanding of cancer. Naked mole rat (NMR, ) is an exceptionally long-lived and cancer-resistant rodent; however, whether lncRNAs play roles in cancer resistance in this seductive species remains unknown.

Results: In this study, we developed a pipeline and identified a total of 4422 lncRNAs across the NMR genome based on 12 published transcriptomes.

Perceiving and interacting affordances: a new model of human-affordance interactions.

This article introduces a new affordance framework for humans and human design. Based on previous important concepts in product design-affordance, signifier, and product semantics, the authors propose three new concepts to illustrate how people perceive affordance. According to the model, perceptual probability of affordance is the probability that the public can perceive a certain affordance; perceptual threshold of affordance is the threshold at which affordance can be perceived by a person and changed by perceptual information; and situations, in which interactions between affordances and people exist, are crucial influences on human-affordance interactions.

4,6-Bis[4-(benzyl-sulfan-yl)styr-yl]-2-(methyl-sulfan-yl)pyrimidine.

The title compound, C(35)H(30)N(2)S(3), has been synthesized by a solvent-free reaction. The mol-ecule exhibits an E,E configuration, the benzene rings and pyrimidine rings being located on the opposite sides of the C=C bonds. The centroid-centroid separation of 3.