A chromosome-scale assembly of the bilberry genome identifies a complex locus controlling berry anthocyanin composition.

Bilberry (Vaccinium myrtillus L.) belongs to the Vaccinium genus, which includes blueberries (Vaccinium spp.) and cranberry (V.

Exploring GNSS Crowdsourcing Feasibility: Combinations of Measurements for Modeling Smartphone and Higher End GNSS Receiver Performance.

GNSS receiver data crowdsourcing is of interest for multiple applications, e.g., weather monitoring.

Sub-classification based specific movement control exercises are superior to general exercise in sub-acute low back pain when both are combined with manual therapy: A randomized controlled trial.

Background: Clinical guidelines recommend research on sub-groups of patients with low back pain (LBP) but, to date, only few studies have been published. One sub-group of LBP is movement control impairment (MCI) and clinical tests to identify this sub-group have been developed. Also, exercises appear to be beneficial for the management of chronic LBP (CLBP), but very little is known about the management of sub-acute LBP.

Efficacy of movement control exercises versus general exercises on recurrent sub-acute nonspecific low back pain in a sub-group of patients with movement control dysfunction. Protocol of a randomized controlled trial.

Background: Practice guidelines recommend various types of exercise for chronic back pain but there have been few head-to-head comparisons of these interventions. General exercise seems to be an effective option for management of chronic low back pain (LBP) but very little is known about the management of a sub-acute LBP within sub-groups. Recent research has developed clinical tests to identify a subgroup of patients with chronic non-specific LBP who have movement control dysfunction (MD).

Pore-polymer interaction reveals nonuniversality in forced polymer translocation.

We present a numerical study of forced polymer translocation by using two separate pore models. Both of them have been extensively used in previous forced translocation studies. We show that variations in the pore model affect the forced translocation characteristics significantly in the biologically relevant range of the pore force, i.

Unforced polymer translocation compared to the forced case.

We present results for unforced polymer translocation from simulations using Langevin dynamics in two dimensions (2D) to four dimensions and stochastic rotation dynamics supporting hydrodynamic modes in three dimensions (3D). We compare our results to forced translocation and a simplified model where the polymer escapes from an infinite pore. The simple model shows that the scaling behavior of unforced translocation is independent of the dimension of the side to which the polymer is translocating.

Critical evaluation of the computational methods used in the forced polymer translocation.

In forced polymer translocation, the average translocation time tau scales with respect to pore force f and polymer length N as tau approximately f;{-1}N;{beta} . We demonstrate that an artifact in the Metropolis Monte Carlo method resulting in breakage of the force scaling with large f may be responsible for some of the controversies between different computationally obtained results and also between computational and experimental results. Using Langevin dynamics simulations we show that the scaling exponent beta View Article and Find Full Text PDF

Polymer scaling and dynamics in steady-state sedimentation at infinite Péclet number.

We consider the static and dynamical behavior of a flexible polymer chain under steady-state sedimentation using analytic arguments and computer simulations. The model system comprises a single coarse-grained polymer chain of N segments, which resides in a Newtonian fluid as described by the Navier-Stokes equations. The chain is driven into nonequilibrium steady state by gravity acting on each segment.

Optimization of aqueous-based film coating of tablets performed by a side-vented pan-coating system.

The purpose of this research was to characterize the aqueous-based hydroxypropylmethylcellulose (HPMC) film coating of tablets utilizing a laboratory-scale side-vented pan-coating apparatus (Thai coater). The process and apparatus parameters of potential importance with respect to the final film quality were evaluated by using fractional factorial design (2(6-2)IV) and the process was optimized using response surface methodology (central composite design). Rotating speed of the pan was identified as a major parameter with respect to film thickness (weight increase; p < 0.

Behaviour of resolution by changing solvent strength and selectivity in the 'PRISMA' model using reversed-phase HPLC for biogenic amines.

The retention behaviour of 17 dansylated biogenic amines in 6 linear gradients at 13 solvent combinations, expressed by the selectivity points (Ps) according to the 'PRISMA' model, was investigated. The dependence between the retention times (tr) and different gradients was examined. Three dimensional resolution (Rs) maps for each peak-pair in the different gradients at the 13 selectivity points were constructed, and the affect of the gradients on separation were investigated.