Enhancing adapted physical activity training for community organizations: co-construction and evaluation of training modules.

Community-based physical activity programmes benefit persons with disabilities. However, there is a lack of evidence-based tools to support kinesiologists' training in such programmes. This study aimed to co-create and evaluate physical activity training modules for community-based adapted physical activity (APA) programmes.

Trends and Clinical Outcomes of Fungal Keratitis in Canada: A 20-year Retrospective Multicentre Study.

Purpose: An increase in fungal and particularly filamentous keratitis has been observed in many geographic areas, mostly in contact lens wearers. This study seeks to characterize long-term trends in fungal keratitis in a continental climate area to provide guidance for diagnosis and treatment.

Design: Retrospective multicentric case series.

Rapid, iterative syntheses of unsymmetrical di- and triarylboranes from crystalline aryldifluoroboranes.

A one-pot procedure to synthesise aryldifluoroboranes, ArBF, from bench-stable arylsilanes is presented. These ArBF react conveniently with aryllithium reagents to form unsymmetrical ArAr'BF and BArAr'Ar'' in high yield. Examples of all three classes of borane have been characterised crystallographically, allowing for elucidation of geometric and crystal packing trends in crystalline ArBF.

Perception of Canadian ophthalmologists on immediately sequential bilateral cataract surgery: insights and implications.

Objective: To evaluate the perception of immediately sequential bilateral cataract surgery (ISBCS) among Canadian ophthalmologists.

Design: An anonymous survey was sent to all active members of the Canadian Ophthalmological Society.

Methods: Basic demographic information, cataract surgery practice patterns, and perceived advantages, disadvantages, and concerns regarding ISBCS were collected from respondents.

Achieving Control over the Reduction/Coupling Dichotomy of N by Boron Metallomimetics.

We report a detailed computational and experimental study of the fixation and reductive coupling of dinitrogen with low-valent boron compounds. Consistent with our mechanistic findings, the selectivity toward nitrogen fixation or coupling can be controlled through either steric bulk or the reaction conditions, allowing for the on-demand synthesis of nitrogen chains. The electronic structure and intriguing magnetic properties of intermediates and products of the reaction of dinitrogen with borylenes are also elucidated using high-level computational approaches.

Perception of visual outcomes in patients after delayed compared with immediately sequential bilateral cataract surgery.

Purpose: To evaluate patient-reported visual outcomes of immediately sequential bilateral cataract surgery (ISBCS) compared with delayed sequential bilateral cataract surgery (DSBCS).

Setting: Tertiary university teaching hospital of Laval University, Quebec City, Canada.

Design: Prospective observational cohort study.

Intraocular methotrexate for epithelial downgrowth: long-term outcomes in a multicentre case series.

Background/aims: Sheet-like type of epithelial downgrowth (EDG) is not easily amenable to surgical excision. We describe long-term outcomes in patients with EDG treated with intraocular methotrexate (MTX).

Methods: This is a retrospective, multicentric case series including 10 eyes (nine patients) treated with intraocular MTX for sheet-like EDG.

Immediately sequential bilateral cataract surgery: an academic teaching center's experience.

Purpose: To evaluate the safety and outcomes of immediately sequential bilateral cataract surgery (ISBCS) at a Canadian academic teaching center.

Setting: Tertiary university teaching hospital of Laval University, Quebec City, Canada.

Design: Retrospective cohort study.

A retrospective study of adverse effects of mycophenolate mofetil administration to dogs with immune-mediated disease.

Background: Information regarding adverse events (AEs) of mycophenolate mofetil (MMF) is limited.

Objectives: To evaluate the types and frequency of potential AEs of MMF in dogs with immune-mediated disease.

Animals: One hundred thirty-one dogs treated with MMF for management of suspected immune-mediated disease.

Conjunctival Infiltration in a Child as a Rare Manifestation of IgG4-Related Disease.

Purpose: Ocular manifestations of immunoglobulin G4 (IgG4)-related disease are common in children although remain ill-defined because of the disease's rarity. We describe a pediatric case of IgG4-related orbital disease (IgG4-ROD) who presented with persistent conjunctival infiltration before developing lacrimal gland enlargement 3 years later.

Methods: This was a case report.

Towards the catalytic activation of inert small molecules by main-group ambiphiles.

The activation of very inert small molecules generally requires highly reactive activating species, but the high energy of these species makes their regeneration, and thus also catalytic turnover of the reaction, difficult to achieve. Here, the authors highlight the formidable challenge of overcoming the tradeoff between activating power and catalytic turnover in the context of main-group ambiphiles.

One-pot, room-temperature conversion of dinitrogen to ammonium chloride at a main-group element.

The industrial reduction of dinitrogen (N) to ammonia is an energy-intensive process that consumes a considerable proportion of the global energy supply. As a consequence, species that can bind N and cleave its strong N-N bond under mild conditions have been sought for decades. Until recently, the only species known to support N fixation and functionalization were based on a handful of metals of the s and d blocks of the periodic table.

2,2'-Bipyridyl as a Redox-Active Borylene Abstraction Agent.

2,2'-Bipyridyl is shown to spontaneously abstract a borylene fragment (R-B:) from various hypovalent boron compounds. This process is a redox reaction in which the bipyridine is reduced and becomes a dianionic substituent bound to boron through its two nitrogen atoms. Various transition metal-borylene complexes and diboranes, as a well as a diborene, take part in this reaction.

Ethical research engagement with Indigenous communities.

Introduction: Canada's colonial policies and practices have led to barriers for Indigenous older adults' access to healthcare and research. As a result, there is a need for Indigenous-led research and culturally safe practices. Morning Star Lodge is developing a training module to assist AgingTech researchers on ethical, culturally safe ways to engage Indigenous communities.

Transition-metal-carbene-like intermolecular insertion of a borylene into C-H bonds.

We demonstrate that, in analogy to transition-metal carbene chemistry, [(OC)5Mo[double bond, length as m-dash]BN(SiMe3)2] facilitates intermolecular transfer of the borylene [:BN(SiMe3)2], which ultimately undergoes insertion into C-H bonds under very mild conditions. The one-pot multiple functionalization of the cyclopentadienyl rings of tungstenocene dihydride is demonstrated using this approach.

Synthesis of unsymmetrical BE and BE heterocycles by borylene insertion into boradichalcogeniranes.

We report the selective insertion of a range of borylene fragments into the E-E bonds (E = S, Se, Te) of cyclic boron dichalcogenides. This method provides facile synthetic access to a variety of symmetrical and unsymmetrical four- and five-membered rings.

Heterodiatomic Multiple Bonding in Group 13: A Complex with a Boron-Aluminum π Bond Reduces CO.

Heterodiatomic multiple bonds have never been observed within Group 13. Herein, we disclose a method that generates [(CAAC)PhB=AlCp ] (1), a complex featuring π bonding between boron and aluminum through the association of singlet fragments. We present the properties of this multiple bond as well as the reactivity of the complex with carbon dioxide, which yields a boron CO complex via an unusual metathesis reaction.

The reductive coupling of dinitrogen.

The coupling of two or more molecules of dinitrogen (N) occurs naturally under the radiative conditions present in the ionosphere and may be achieved synthetically under ultrahigh pressure or plasma conditions. However, the comparatively low N-N single-bond enthalpy generally renders the catenation of the strongly triple-bonded N diatomic unfavorable and the decomposition of nitrogen chains a common reaction motif. Here, we report the surprising organoboron-mediated catenation of two N molecules under near-ambient conditions to form a complex in which a [N] chain bridges two boron centers.

Metallomimetic Chemistry of Boron.

The study of main-group molecules that behave and react similarly to transition-metal (TM) complexes has attracted significant interest in recent decades. Most notably, the attractive idea of replacing the all-too-often rare and costly metals from catalysis has motivated efforts to develop main-group-element-mediated reactions. Main-group elements, however, lack the electronic flexibility of TM complexes that arises from combinations of empty and filled d orbitals and that seem ideally suited to bind and activate many substrates.

Theoretical Calculations for Highly Selective Direct Heteroarylation Polymerization: New Nitrile-Substituted Dithienyl-Diketopyrrolopyrrole-Based Polymers.

Direct Heteroarylation Polymerization (DHAP) is becoming a valuable alternative to classical polymerization methods being used to synthesize π-conjugated polymers for organic electronics applications. In previous work, we showed that theoretical calculations on activation energy (E) of the C⁻H bonds were helpful to rationalize and predict the selectivity of the DHAP. For readers' convenience, we have gathered in this work all our previous theoretical calculations on E and performed new ones.