Do Health Information Sources Influence Health Literacy among Older Adults: A Cross-Sectional Study in the Urban Areas of Western China.

Background: Previous studies have found that the dissemination pattern and delivery mechanism of information can provide crucial resources and empowerment for individuals to the promotion of health literacy. The present study investigates how health information sources are associated with health literacy among older adults in west China, and tries to explain the mechanisms underlying the link between health information sources and health literacy in the Chinese context.

Methods: The cross-sectional study employed a representative sample of 812 urban citizens aged 60 and older in 2017 in Western China.

Internet Addiction of Older Women and Its Relationship With Social Influence and Social Networks Use as a Mediator.

The aim is to analyse the relationship between social influence for Internet use and Internet addiction (IA) in older women, considering the use of Internet-based social networks as a mediator. The participants were 480 older women Internet users. Social influence, frequency of use of social networks and IA (including loss of control and emotional dysregulation) were evaluated.

Sense of Community Mediating Between Age-Friendly Characteristics and Life Satisfaction of Community-Dwelling Older Adults.

The growth of age-friendly community initiatives underscores a paradigmatic shift from the individual to the community, addressing dynamic transactions between people and the environment they are living in. The purpose of the present study is to address the gap in existing research by examining the psycho-social effects of the sense of community in mediating between WHO domains of age-friendliness and the life satisfaction of older adults. Data were obtained from 898 participants in Hong Kong.

The ageing and de-institutionalisation of death-Evidence from England and Wales.

Increasingly, age of death is postponed until very old age, and care of those who are dying is challenged by medical co-morbidities and the presence of dementia. Although most people would prefer to die at home, currently in England and Wales only about 20 per cent of those aged 65 years and over die at home, and this proportion falls to about 10 per cent among those aged over 85 years. To explore recent and likely future trends in age and place of death, mortality statistics from 2006 to 2013 were analysed and projected to 2050 using age- and gender-specific rates.

Future prospects for longevity.

It is acknowledged that the world is ageing at both the individual and population level. Life expectancies at birth have increased for males and females in the more developed economies across the 20th century. The 21st century is expected to see this development continue with life expectancies moving towards 100 years.

Income inequality and health: importance of a cross-country perspective.

This paper uses a unique dataset-containing information collected in 2006 on individuals aged 40-79 in 21 countries throughout the world to examine whether individual income, relative income in a reference group, and income inequality are related to health status across middle/low and high-income countries. The dependent variable is self-assessed health (SAH), and as a robustness check, activities of daily living (ADL) are considered. The focus is particularly on assumptions regarding an individual's reference group and on how the estimated relationships depend on the level of economic development.

Metabolism of terfenadine associated with CYP3A(4) activity in human hepatic microsomes.

Terfenadine (Seldane) undergoes extensive metabolism to form azacyclonol and terfenadine alcohol. Terfenadine alcohol is subsequently metabolized to azacyclonol and terfenadine acid. Although testosterone 6 beta-hydroxylation [CYP3A(4)] has been shown to be the principal enzyme involved in the first step in terfenadine's biotransformation (formation of azacyclonol and terfenadine alcohol), the enzymes catalyzing the subsequent metabolic steps in the conversion of terfenadine alcohol to azacyclonol and terfenadine acid have not been identified.

The situation of the elderly in Denmark.

In this paper, basic socio-economic and demographic data about the elderly are presented. Since the younger elderly are more active and have better health than previous generations and since the older elderly comprise the group likely to make most demands on society, the paper concentrates mainly on those aged 75 and over. The demography of the elderly is considered by way of introduction, followed by more specific topics of particular interest for the group in question, such as finance, household composition, institutions and service, health and family structure.

Regioselectivity of metabolic activation of acetylenic steroids by hepatic cytochrome P450 isozymes.

Liver cytochrome P450 monooxygenases (P450), a group of isozymes that catalyze the reductive cleavage of molecular oxygen, dominate hepatic metabolism of xenobiotic lipophilic substances. These P450 enzymes exhibit broad and overlapping substrate specificities, in contrast to the P450 isozymes of the steroid biosynthetic pathways, which are highly substrate specific. Hepatic heme pigments, N-alkylated porphyrins, accumulate following the self-catalyzed destruction of P450 by the metabolic activation of 17 alpha-ethynyl steroids.

Ageing and economic welfare.

"The purpose of the present paper is to seek to elucidate the effects of recent and future population development upon the economic welfare of the Danish population as a whole, but especially of the elderly." It is shown that the proportion of the elderly in the total population has increased from 10 percent in 1900 to 20 percent in 1984 and is likely to increase to 21 percent in 2000 and 30 percent in 2025. The consequent increase in the dependency burden on those of working age is examined.

Dose related induction of the drug metabolizing enzymes of rat liver by cilobamine.

Cilobamine , an antidepressant, was investigated for its influence on the hepatic drug metabolizing enzymes ( DME ) of male Charles River CD rats. Cilobamine doses (3, 10, 30, 100, and 300 mg/kg po, as free base) were compared to sodium phenobarbital (PB) doses (3, 10, 30, 100, and 200 mg/kg po, as free acid). Compounds were given daily for 4 days and all tests were done on Day 5.

Demographic ageing in Denmark in the twentieth century.

"In the twentieth century the Danish population has, in demographic terms, aged considerably, the proportion of the population aged 60 years and over having increased from 9.8 to 19.6 per cent.

Metabolic disposition of terfenadine in laboratory animals.

Alpha-[4-(1,1-Dimethylethyl)phenyl]-4-(hydroxydiphenylmethyl)-1- piperidinebutanol (terfenadine, RMI 9918, Triludan, Teldane, resp.), a clinically effective antihistamine, with little or no central nervous system effects, was investigated in order to understand its metabolic disposition. These 14C-terfenadine studies were performed in laboratory animals, principally the rat, and also in beagle dog and monkey (Macaca mulatta).

Bioavailability of terfenadine in man.

Fourteen normal male subjects were given either 60mg or 180mg of terfenadine suspension in a randomized two-way crossover study. Peak plasma concentrations of 1.544 +/- 0.

Radioimmunoassay for terfenadine in human plasma.

A radioimmunoassay procedure was developed for the antihistamine terfenadine (alpha[4-(1,2-dimethylethyl)phenyl]-4-(hydroxydiphenylmethyl)-1-piperidinebutanol). The keto analog of terfenadine was converted to its O-carboxymethyloxime derivative, which was conjugated to bovine thyroglobulin by a mixed anhydride technique. Rabbits were immunized with the resulting conjugate, and antiserums capable of binding radiolabeled terfenadine were obtained.

Identification of basic metabolites of 4-[4-(p-chlo- robenzoyl)piperidino]-4'-fluorobutyrophenone, an experimental neuroleptic agent.

Two metabolites of 4-[4-(p-(chlorobenzoyl)piperidino]-4'-fluorobutyrophenone (RMI 9901) as well as unchanged drug, have been identified in the urine of rats following oral administration of the drug. Analysis of basic urine extracts by combined gas chromatography-mass spectrometry was employed for metabolite identification. N-dealkylation appears to be a major metabolic pathway and results in formation of 4-(p-chlorobenzoyl)piperidine (I).

Decrease in the activity of the drug-metabolizing enzymes of rat liver following the administration of tilorone hydrochloride.

Tilorone hydrochloride, 2,7-bias(2-(diethylamino)ethoxy(fluoren-9-one dihydrochloride, has been studied to determine its effect on the drug-metabolizing enzymes of the liver of male Charles River CD strain rats. Single and multiple doses of tilorone-HCl, 100 mg/kg/day po, were used. Most experiments were performed 24 hr after the last dose, except for a study 5 hr after dosing, and those in which the duration of effects of tilorone hydrochloride were determined.

Poisoning with delayed-release tablets. Treatment of Debendox poisoning with purgation and dialysis.

Accidental poisoning with delayed-release tablets causes symptoms at a time when the tablets can no longer be retrieved from the stomach. A child died from eating 23 tablets of Debendox, which is a delayed-release tablet containing dicyclomine and doxylamine. A second child survived a similar overdose, having been subjected to vigorous purgation and peritoneal dialysis.