Publications by authors named "Leena Ziane"

Article Synopsis
  • - Pavlovian fear conditioning research has primarily focused on male rodents and the freezing response, but new findings reveal that female rodents exhibit a different response called "darting," characterized by rapid escape movements.
  • - Darting females (Darters) show less freezing than males and Non-darters, and they move faster when exposed to foot shocks, raising questions about the underlying mechanisms of these responses.
  • - Further investigation showed that Darters are not more sensitive to aversive stimuli compared to Non-darters and males; instead, they might be less reactive in certain cases, highlighting the need to consider individual responses in fear conditioning studies.
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Pavlovian fear conditioning is a widely used tool that models associative learning in rodents. For decades the field has used predominantly male rodents and focused on a sole conditioned fear response: freezing. However, recent work from our lab and others has identified darting as a female-biased conditioned response, characterized by an escape-like movement across a fear conditioning chamber.

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Neurogliaform cells are a distinct type of GABAergic cortical interneurons known for their 'volume transmission' output property. However, their activity and function within cortical circuits remain unclear. Here, we developed two genetic tools to target these neurons and examine their function in the primary visual cortex.

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Neurogliaform cells are a distinct type of GABAergic cortical interneurons known for their "volume transmission" output property. However, their activity and function within cortical circuits remain unclear. Here, we developed two genetic tools to target these neurons and examine their function in the primary visual cortex.

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