Biological metal organic framework (bio-MOF) of glucoamylase with enhanced stability.

The handling of conventional enzyme- metal organic framework (MOF) composites is big challenge due to their nano-sized and lightweight structure with low density. Also, conventional MOFs are derived from non-renewable petroleum feedstock which makes them inherent toxic and non-biodegradable. To overcome these difficulties, recently, green, renewable framework material composite, biological metal-organic frameworks (bio-MOFs) have intrigued as a novel class of porous materials.

Enzyme embedded metal organic framework (enzyme-MOF): De novo approaches for immobilization.

The porous material has been considered as a potential candidate for immobilizing enzymes. Recently, metal organic framework (MOF) has been emerged as a hybrid organic inorganic material with unique intrinsic properties such as well-defined pore structure, excellent chemico-thermal stability, and extremely high surface areas which make them as a suitable scaffold for enzyme immobilization. The outstanding improvement in catalytic performance, high enzyme loading capacity, remarkable interaction between enzyme and MOF are the key features of the novel enzyme-MOF biocomposites.

Entrapment of surfactant modified lipase within zeolitic imidazolate framework (ZIF)-8.

Mostly, enzyme activity is reduced after immobilization of enzyme within MOF due to unfavourable conformational changes occurred during the immobilization procedure. In this context, lipase was activated by surfactants (in order to get a highly active enzyme) followed by encapsulation within zeolitic imidazolate framework (ZIF)-8 via one-pot facile self-assembly method. The prepared lipase-SDS ZIF-8 exhibited 250% enhanced activity compared to native form.

Community mobilization in Mumbai slums to improve perinatal care and outcomes: a cluster randomized controlled trial.

Introduction: Improving maternal and newborn health in low-income settings requires both health service and community action. Previous community initiatives have been predominantly rural, but India is urbanizing. While working to improve health service quality, we tested an intervention in which urban slum-dweller women's groups worked to improve local perinatal health.

Community-based health programmes: role perceptions and experiences of female peer facilitators in Mumbai's urban slums.

Community-based initiatives have become a popular approach to addressing the health needs of underserved populations, in both low- and higher-income countries. This article presents findings from a study of female peer facilitators involved in a community-based maternal and newborn health intervention in urban slum areas of Mumbai. Using qualitative methods we explore their role perceptions and experiences.

Cluster-randomised controlled trial of community mobilisation in Mumbai slums to improve care during pregnancy, delivery, postpartum and for the newborn.

Background: The United Nations Millennium Development Goals look to substantial improvements in child and maternal survival. Morbidity and mortality during pregnancy, delivery and the postnatal period are prime obstacles to achieving these goals. Given the increasing importance of urban health to global prospects, Mumbai's City Initiative for Newborn Health aims to improve maternal and neonatal health in vulnerable urban slum communities, through a combination of health service quality improvement and community participation.