Background: The purpose of this study was to investigate and compare three different pit and fissure sealants with different composition to check their effectiveness for sealing ability and microleakage.
Materials & Methods: Total 120 therapeutically extracted premolars devoid of any caries, anomalies or morphogenic diversity were collected and distributed equally in three groups (40 in each). Group - I: Composite based Pit and fissure sealant, Group -II: Compomer- restorative material and GROUP-III: Glass ionomer cement based pit and fissure sealant.