Publications by authors named "LeeAnne Lynch"

Background: Little research exists to support the administration of corticosteroids to pregnant women with diabetes. Pregnant women are often excluded from clinical trials due to concerns of harm to the foetus.

Aim: This study aimed to understand the experiences of women and clinicians of participating in the Prevention of neonatal Respiratory distress with antenatal corticosteroids before Elective Caesarean section in women with Diabetes pilot randomised controlled trial to determine the acceptability of the study protocol.

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Article Synopsis
  • The PRECeDe Pilot Trial aimed to assess the feasibility of a larger study on whether antenatal corticosteroids could help pregnant women with diabetes by administering the treatment before an elective caesarean section.* -
  • Conducted in Melbourne, Australia, the trial randomized pregnant women with pre-gestational or gestational diabetes to receive either betamethasone or a saline placebo before their scheduled cesarean.* -
  • Of 537 eligible women, 47 participated, showing initial support for conducting a larger trial on the effectiveness of corticosteroids in reducing newborn respiratory issues related to diabetes.*
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Introduction: The U.S. Army's Soldier 2020 program, which started in January 2016, was designed to achieve full integration of women in all military occupational specialties.

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Venous thromboembolic disease (VTE) risk increases five-fold antenatally and 14-fold during the puerperium. Obesity significantly increases this risk. The D-dimer assay and more novel Calibrated Automated Thrombogram (CAT) assay laboratory tests display potential for use in VTE risk stratification in pregnancy, although to date, research in the performance characteristics of these tests in obese and nonobese pregnant populations is limited.

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Background: Seasonal influenza and pertussis cause significant morbidity and mortality among expectant mothers and infants. Vaccination during the antenatal period is an important public health intervention, minimising rates of maternal, neonatal and infant infection.

Aims: The primary aim of this project was to establish the rates of antenatal vaccine uptake.

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The Department of Defense (DoD) generates influenza vaccine effectiveness (VE) estimates each season. The Armed Forces Health Surveillance Branch Air Force (AFHSB-AF) satellite, Naval Health Research Center Operational Infectious Disease Directorate at the Naval Health Research Center (NHRCOID), and the Armed Forces Health Surveillance Branch (AFHSB) all conduct influenza surveillance and perform test-negative case-control analyses to estimate seasonal influenza VE for DoD populations. The mid-season estimates contribute to the aggregate data utilized by the Food and Drug Administration's Vaccine and Related Biological Products Advisory Committee to select the composition of the influenza vaccine for the next influenza season.

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