Transatlantic medical consultation and second opinion in pediatric cardiology has benefit past patient care: A case study in videoconferencing.

Background: Telemedicine is a rapidly evolving form of modern information and communication technology used to deliver clinical services and educational activities.

Objective: The aim of this article is to report and analyze our experience with transatlantic consultation via videoconferencing in pediatric cardiology.

Methods: In February, 2013, videoconferencing project was launched between a medium-volume pediatric cardiac center in Bratislava, Slovakia and subspecialty experts from a high-volume pediatric cardiac program at The Children's Hospital of Philadelphia (CHOP), USA.

Implementation of a Clinical Pathway for Chest Pain in a Pediatric Emergency Department.

Objective: To evaluate the impact of a pediatric emergency department (ED) chest pain clinical pathway on resource utilization.

Methods: Motivated by perceived overuse of cardiology consultation for non-cardiac chest pain in the ED, clinicians from the Divisions of Cardiology and Emergency Medicine collaboratively developed a chest pain clinical pathway, educated staff, and implemented the pathway on March 1, 2014. We reviewed records of children aged 3 to 18 years without prior diagnoses of heart disease who presented to the ED with chest pain between March 1, 2013, and April 22, 2015.

Evaluating the implementation of a primary care weight management toolkit.

Objective: With over one-third of adults in the United States classified as obese, new recommendations call for screening all adults for obesity at outpatient visits. The UW Health Fox Valley Clinic does not actively screen for obesity. The objective of this project was to test the feasibility of an obesity screening and brief intervention protocol.

Genotype- and mutation site-specific QT adaptation during exercise, recovery, and postural changes in children with long-QT syndrome.

Background: Exercise stress testing has shown diagnostic utility in adult patients with long-QT syndrome (LQTS); however, the QT interval adaptation in response to exercise in pediatric patients with LQTS has received little attention.

Methods And Results: One-hundred fifty-eight patients were divided into 3 groups: Those with LQTS type 1 (LQT1) or LQTS type 2 (LQT2) and normal control subjects without cardiovascular disease. Each patient underwent a uniform exercise protocol with a cycle ergometer followed by a 9-minute recovery phase with continuous 12-lead ECG monitoring.

A pilot study of the feasibility of heart screening for sudden cardiac arrest in healthy children.

Background: In children, sudden cardiac arrest (SCA) is associated with structural and electrical cardiac abnormalities. No studies have systematically screened healthy school children in the United States for conditions leading to SCA to identify those at risk.

Methods: From June 2006 to June 2007, we screened 400 healthy 5- to 19-year-olds (11.

Congenital long QT syndrome and 2:1 atrioventricular block: an optimistic outcome in the current era.

Background: Previous studies of patients with long QT syndrome (LQTS) and 2:1 atrioventricular block (AVB) have reported a mortality rate greater than 50% during infancy.

Objective: The purpose of this study was to determine the outcome of this high-risk population in the current era.

Methods: A retrospective study from four tertiary care pediatric centers assessed patients with congenital LQTS and 2:1 AVB from January 2000 to January 2009.

Molecular cloning and characterisation of p15(CDK-BP), a novel CDK-binding protein.

The suc1/Cks proteins are well-conserved regulatory components of cyclin-dependent kinases 1 and 2 (CDK1/2). These small molecular mass proteins form a stable complex with CDK1/2 and are essential for normal regulation of CDKs during the cell division cycle and for degradation of p27(kip1). Despite the high degree of homology between the nine known CDKs, only CDK1, CDK2 and, to a lesser extent, CDK3 are able to bind to the suc1/Cks proteins.