Destructive and Constructive Interparental Conflict, Parenting Stress, Unsupportive Parenting, and Children's Insecurity: Examining Short-Term Longitudinal Dyadic Spillover and Crossover Process.

Based on emotional security, stress, and spillover and crossover theories, this study aimed to examine the indirect pathways between destructive and constructive interparental conflict, parenting stress, unsupportive parenting, and child insecurity six months later. Using data from two time points beginning when Korean children ( = 159) were approximately 3-5 years old, two dual-mediation models of the relevant variables were constructed. The results indicate that destructive conflict is associated with higher levels of parenting stress, whereas constructive conflict is associated with lower levels of stress.

The three-dimensional genome drives the evolution of asymmetric gene duplicates via enhancer capture-divergence.

Previous evolutionary models of duplicate gene evolution have overlooked the pivotal role of genome architecture. Here, we show that proximity-based regulatory recruitment by distally duplicated genes is an efficient mechanism for modulating tissue-specific production of preexisting proteins. By leveraging genomic asymmetries, we performed a coexpression analysis on tissue data to show the generality of enhancer capture-divergence (ECD) as a significant evolutionary driver of asymmetric, distally duplicated genes.

Proximity to Explosive Synchronization Determines Network Collapse and Recovery Trajectories in Neural and Economic Crises.

When complex systems move away from criticality-a balance between order and chaos-they are no longer optimized. Furthermore, when criticality is lost too quickly, or recovery is delayed, system damage can result. However, the mechanism for these abnormally fast or slow critical transitions remains unknown.

Assembly of Custom Implant and Ready-Made Distractor for Precise Maxillary Movement Vector Control in Cleft Patient With Midfacial Hypoplasia.

This study presents a novel approach for maxillary advancement in a patient with cleft lip and palate, utilizing the assembly of a custom titanium implant and a ready-made distractor. The patient exhibited significant maxillary hypoplasia and had concerns regarding the possible deterioration of hypernasality after conventional surgical methods. Distraction osteogenesis was initiated to address these challenges.

Experiences With Genitourinary Syndrome of Menopause and Barriers to Vaginal Estrogen Usage Reported by a National Sample of 1500 Women.

Objective: To investigate women's experiences with genitourinary syndrome of menopause (GSM) and vaginal estrogen therapy (VET), including barriers, awareness, and knowledge, and to report current trends and findings on GSM and VET to address barriers to care.

Methods: A survey on GSM and VET was posted on the ResearchMatch website. Eligible participants were women ≥ 40 years of age.

Growth of soil ammonia-oxidizing archaea on air-exposed solid surface.

Soil microorganisms often thrive as microcolonies or biofilms within pores of soil aggregates exposed to the soil atmosphere. However, previous studies on the physiology of soil ammonia-oxidizing microorganisms (AOMs), which play a critical role in the nitrogen cycle, were primarily conducted using freely suspended AOM cells (planktonic cells) in liquid media. In this study, we examined the growth of two representative soil ammonia-oxidizing archaea (AOA), EN76 and "" MY2, and a soil ammonia-oxidizing bacterium, ATCC 19718 on polycarbonate membrane filters floated on liquid media to observe their adaptation to air-exposed solid surfaces.

". Nitrosocosmicus" members are the dominant archaea associated with plant rhizospheres.

Unlabelled: Archaea catalyzing the first step of nitrification in the rhizosphere possibly have an influence on plant growth and development. In this study, we found a distinct archaeal community, dominated by ammonia-oxidizing archaea (AOA), associated with the root system of pepper ( L.) and ginseng plants ( C.

Treatment with novel topoisomerase inhibitors in Ewing sarcoma models reveals heterogeneity of tumor response.

Introduction: The topoisomerase 1 (TOP1) inhibitor irinotecan is a standard-of-care agent for relapsed Ewing sarcoma (EWS), but its efficacy is limited by chemical instability, rapid clearance and reversibility, and dose-limiting toxicities, such as diarrhea. Indenoisoquinolines (IIQs) represent a new class of clinical TOP1 inhibitors designed to address these limitations.

Methods: In this study, we evaluated the preclinical efficacy of three IIQs (LMP400, LMP744, and LMP776) in relevant models of EWS.

Computational analysis on 3D airway model of obstructive sleep apnea patient for optimal maxillomandibular advancement.

Obstructive sleep apnea (OSA) can have many adverse effects on people's health, including cognitive decline and high blood pressure. Typical surgical treatment methods include the commonly performed uvulopalatopharyngoplasty and the highly successful maxillomandibular advancement (MMA). These surgical methods are more effective than non-surgical methods because they widen the airway where a collapse has occurred through direct treatment.

Accuracy of a Smart Diaper System for Nursing Home Residents for Automatically Detecting Voided Volume: Instrument Validation Study.

Background: Diapers are commonly used by older patients with urination disorders. A smart diaper system (SDS) may be able to estimate the weight of urine comparably to conventional measurements made by weighing diapers.

Objective: The aim of the current research is to determine the degree of accuracy of an SDS technology specifically designed for the management of urination routines and the use of incontinence pads in older adults.

Morphometric analysis of the hard palate in sex estimation among koreans using three-dimensional computed tomography.

Accurate sex estimation is crucial for comprehensive analysis of the biological profiles of unidentified human skeletal remains. However, there is a notable lack of research specifically addressing the morphometrics of the hard palate. Therefore, this study aimed to derive discriminant equations using the hard palate and assess their applicability for sexing partial skeletal remains in a contemporary Korean population.

Sustainable Formate Production via Highly Active CO Hydrogenation Using Porous Organometallic Polymer with Ru-PNP Active Sites.

Efforts to combine the advantages of homogeneous catalysts in terms of activity with the ease of separation process offered by heterogeneous catalysts continue to be actively pursued in the field of catalyst development. Heterogeneous catalysts were synthesized from Ru-MACHO organometallic compounds, recognized for their high hydrogenation catalytic activity linked to the active site of the Ru-PNP motif, through direct polymerization utilizing the Friedel-Crafts reaction. These catalysts were then applied for the conversion of greenhouse gas carbon dioxide (CO) into formate via hydrogenation, exhibited with a record-high turnover frequency of 31,700 and a productivity of 36,100 kg/(kg ⋅ d).

Innovative Approach to Severe Esthetic Zone Trauma: Integrating Root Submergence With Guided Bone Regeneration.

Objective: Acute traumatic defects in the esthetic zone pose a significant challenge in dental implant rehabilitation, requiring innovative techniques to achieve optimal functional and esthetic outcomes. This article investigates the use of a novel combination of root submergence and guided bone regeneration (GBR) to address these defects. The goal is to evaluate the potential of this integrated approach for achieving predictable bone regeneration and long-term tissue stability.

Synthesis of Chiral Ag, Pd, and Pt Helicoids inside Chiral Silica Mold.

Chiral inorganic nanomaterials hold significant promise for various applications, including enantioselective catalysis, polarization-controlling optical devices, metamaterials, and enantioselective molecular sensors. In our previous work, we presented a method for synthesizing chiral Au 432 helicoid III (Au helicoids) from peptides and amino acids, where helical gaps are intricately arranged with 432 symmetry within single cubic nanoparticles. In this study, we have achieved the fabrication of chiral silica molds through Au etching subsequent to the silica coating of Au helicoids.

Clinical validity and precision of deep learning-based cone-beam computed tomography automatic landmarking algorithm.

Purpose: This study was performed to assess the clinical validity and accuracy of a deep learning-based automatic landmarking algorithm for cone-beam computed tomography (CBCT). Three-dimensional (3D) CBCT head measurements obtained through manual and automatic landmarking were compared.

Materials And Methods: A total of 80 CBCT scans were divided into 3 groups: non-surgical (39 cases); surgical without hardware, namely surgical plates and mini-screws (9 cases); and surgical with hardware (32 cases).

Exploring the influence of cell configurations on Cu catalyst reconstruction during CO electroreduction.

Membrane electrode assembly (MEA) cells incorporating Cu catalysts are effective for generating C chemicals via the CO reduction reaction (CORR). However, the impact of MEA configuration on the inevitable reconstruction of Cu catalysts during CORR remains underexplored, despite its considerable potential to affect CORR efficacy. Herein, we demonstrate that MEA cells prompt a unique reconstruction of Cu, in contrast to H-type cells, which subsequently influences CORR outcomes.

Biocompatibility and dimensional stability through the use of 3D-printed scaffolds made by polycaprolactone and bioglass-7: An in vitro and in vivo study.

Purpose: This experiment aimed to observe the differences in biological properties by producing BGS-7 + PCL scaffolds with different weight fractions of BGS-7 through 3D printing and to confirm whether using the scaffold for vertical bone augmentation is effective.

Materials And Methods: Cube-shaped bioglass (BGS-7) and polycaprolactone (PCL) scaffolds with different weight fractions (PCL alone, PCL with 15% and 30% BGS-7) are produced using 3D printing. The surface hydroxyapatite (HA) apposition, the pH change, proliferation and attachment assays, and various gene expression levels are assessed.

Hypertension Prevalence among Hispanics/Latinos of Dominican Background: A Transnational Comparison of HCHS/SOL and ENPREFAR-HAS-17.

Background: Hispanics/Latinos of Dominican background living in United States (US) have the highest hypertension prevalence compared with other Hispanic/Latino persons.

Objective: To understand cardiovascular health among Dominicans, we evaluated hypertension prevalence and risk factors among Dominicans from the US and Dominican Republic (DR) using data from Hispanic Community Health Study/ Study of Latinos [HCHS/SOL] and the Prevalencia de Hipertension Arterial y Factores de Riesgo Cardiovasculares en la República Dominicana al 2017 (ENPREFAR-HAS 17) study.

Methods: Hypertension was defined as blood pressure ≥140/90 mmHg, self-reported hypertension, or antihypertensive use.

Comparative Analysis of the Characteristics of Two Hardy Kiwifruit Cultivars ( cv. Cheongsan and Daebo) Stored at Low Temperatures.

A cold storage system is useful for maintaining the quality of hardy kiwifruit. However, extended cold storage periods inevitably result in cold stress, leading to lower fruit marketability; the severity of chilling injury depends on fruit types and cultivars. In this study, the impact of cold storage conditions on the physicochemical properties and antioxidant capacity of two phenotypically different hardy kiwifruit cultivars-'Cheongsan' (large type) and 'Daebo' (small type)-stored at low (L; 3 °C, relative humidity [RH]; 85-90%) and moderate-low (ML; 5 °C, RH; 85-90%) temperatures was determined.

Geometric changes and clinical risk factors from aortic arch to proximal internal carotid artery between normal subjects and moderate right carotid plaques.

The anatomical features spanning from the aortic arch to the proximal carotid artery and the associated cardiovascular risks might significantly influence the development of right carotid plaque. Our research aimed to compare these anatomical and risk factors between individuals with no carotid plaque and those with moderate right-side carotid plaque within a Korean cohort. We conducted a retrospective, cross-sectional analysis involving 413 participants, categorized into a normal group (n = 339) and a right moderate carotid plaque group (defined as > 50% stenosis based on NASCET criteria) (n = 74).

Microneedle patch casting using a micromachined carbon master for enhanced drug delivery.

For successful treatment of diseases, sufficient therapeutics must be provided to the body. Microneedle applications in therapeutic delivery and analytics sampling are restricted because of various issues, including smaller area for drug loading and analytics sampling. To achieve sufficient drug loading and analytics sampling and improve drug penetration while maintaining painless administration, patch-type microneedle arrays were designed and fabricated using polymer casting from a conical cavity mold.