Publications by authors named "Lee Shien Low"

Article Synopsis
  • The study investigated how recombinant human growth hormone (rhGH) treatment affects brain structure volumes in children with isolated growth hormone deficiency (IGHD), focusing on areas like the pituitary gland, hippocampus, and amygdala.
  • Eight IGHD subjects underwent MRI scans before and after an average of 1.8 years of rhGH therapy, comparing their brain structures to age-matched controls.
  • Results showed that while IGHD subjects initially had smaller volumes in certain brain areas, rhGH therapy led to normalization of these volumes, suggesting its potential for not only physical growth but also brain development.
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