Publications by authors named "Lee Ann Jarrett"
Background: The late effect continuum of lymphedema and fibrosis (LEF) affects more than 70% of patients after treatment for head and neck cancer (HNC). LEF is associated with symptom burden and decreased function and quality of life. Although surveillance imaging is common posttreatment, objective assessment of soft tissues is not, likely due to the lack of objective evaluation methods and understanding of the significance of LEF.
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- The study examines how methamphetamine (METH) affects core body temperature, focusing on how tolerance develops with chronic use and the role of ambient temperature.
- Rats were treated with varying doses of METH in controlled temperature settings, and their core temperatures were monitored for 12 days to assess changes over time and under different conditions.
- Findings indicate that peak temperature responses to METH occur at different times based on dosage, that chronic use leads to reduced temperature responses not linked to long-term neurochemical changes, and that the temperature response is characterized by two distinct phases due to different underlying mechanisms.