Quality Measures for Managing Prescription of Antipsychotic Medication Among Youths: Factors Associated With Health Plan Performance.

Objective: This study examined the performance of health plans on two HEDIS measures: metabolic monitoring of children and adolescents prescribed an antipsychotic and use of first-line psychosocial care for children and adolescents prescribed an antipsychotic for a nonindicated use. Plan characteristics and other contextual factors that may be associated with health plan performance were examined to identify potential strategies for improving care.

Methods: The study population included 279 commercial and 169 Medicaid health plans that voluntarily submitted data for care provided in 2016.

Alcohol effects on response inhibition: Variability across tasks and individuals.

Considerable research has investigated the acute effects of alcohol on response inhibition, but a number of issues remain unresolved. Given that most studies use only a single laboratory task to assess inhibition, it is often difficult to determine whether alcohol's effects are task specific or generalize across measures of the same construct. Moreover, relatively few studies have directly compared effects of alcohol under ascending and descending blood alcohol concentrations (BACs), and those that have often failed to disentangle BAC limb effects from the effects of repeated testing.

Acute alcohol effects on set-shifting and its moderation by baseline individual differences: a latent variable analysis.

Aims: To compare the acute effects of alcohol on set-shifting task performance (relative to sober baseline performance) during ascending and descending limb breath alcohol concentration (BrAC), as well as possible moderation of these effects by baseline individual differences.

Design: Shifting performance was tested during an initial baseline and a subsequent drinking session, during which participants were assigned randomly to one of three beverage conditions (alcohol, placebo or control) and one of two BrAC limb conditions [ascending and descending (A/D) or descending-only (D-only)].

Setting: A human experimental laboratory on the University of Missouri campus in Columbia, MO, USA.

Is set shifting really impaired in trait anxiety? Only when switching away from an effortfully established task set.

The current study investigated whether trait anxiety was systematically related to task-set shifting performance, using a task-switching paradigm in which 1 task was more attentionally demanding than the other. Specifically, taking advantage of a well-established phenomenon known as asymmetric switch costs, we tested the hypothesis that the association between trait anxiety and task-set shifting is most clearly observed when individuals must switch away from a more attentionally demanding task for which it was necessary to effortfully establish an appropriate task set. Ninety-one young adults completed an asymmetric switching task and trait-level mood questionnaires.

Stability and change in executive function abilities from late adolescence to early adulthood: A longitudinal twin study.

Executive functions (EFs)-the higher level cognitive abilities that enable us to control our own thoughts and actions-continue to develop into early adulthood, yet no longitudinal study has examined their stability during the important life transition from late adolescence to young adulthood. In this twin study (total N = 840 individuals from 424 families), we examined the stability of individual differences in 3 EF components across a 6-year period, from approximately age 17 years (Wave 1) to 23 years (Wave 2). Specifically, we address the following questions: (a) How stable are individual differences in multiple EFs across this time period? and (b) What (genetic and/or environmental) influences affect stability and change in EFs? Results indicated that individual differences in EFs are quite stable across this 6-year period (phenotypic latent variable correlations ranged from 0.

Toward a comprehensive understanding of executive cognitive function in implicit racial bias.

Although performance on laboratory-based implicit bias tasks often is interpreted strictly in terms of the strength of automatic associations, recent evidence suggests that such tasks are influenced by higher-order cognitive control processes, so-called executive functions (EFs). However, extant work in this area has been limited by failure to account for the unity and diversity of EFs, focus on only a single measure of bias and/or EF, and relatively small sample sizes. The current study sought to comprehensively model the relation between individual differences in EFs and the expression of racial bias in 3 commonly used laboratory measures.

Interaction between family history of alcoholism and Locus of Control in the opioid regulation of impulsive responding under the influence of alcohol.

Background: Naltrexone (NTX) is an opioid antagonist indicated for the treatment of alcoholism, which is not universally effective. Thus, identifying individual predictors of NTX's behavioral effects is critical to optimizing its therapeutic use. Moreover, given the high rate of relapse during treatment for alcoholism, understanding NTX's behavioral effects when combined with moderate ethanol intake is important.

When mental inflexibility facilitates executive control: beneficial side effects of ruminative tendencies on goal maintenance.

Although previous research suggests that depressive ruminators tend to become stuck in a particular mind-set, this mental inflexibility may not always be disadvantageous; in some cases, it may facilitate active maintenance of a single task goal in the face of distraction. To evaluate this hypothesis, we tested 98 college students, who differed in ruminative tendencies and dysphoria levels, on two executive-control tasks. One task emphasized fast-paced shifting between goals (letter naming), and one emphasized active goal maintenance (modified Stroop).

Reversal learning in Parkinson's disease depends on medication status and outcome valence.

We investigated the role of dopamine in distinct forms of reversal shifting by comparing two groups of patients with mild Parkinson's disease (PD), one ON and one OFF their normal dopaminergic medication. In accordance with our previous work, patients ON medication exhibited impaired reversal shifting relative to patients OFF medication. The present results extend previous studies by showing that the medication-induced deficit on reversal shifting was restricted to conditions where reversals were signaled by unexpected punishment.