The Enriched Proanthocyanidin Extract of Ligaria cuneifolia Shows a Marked Hypocholesterolemic Effect in Rats Fed with Cholesterol-Enriched Diet.

Background: Ligaria cuneifolia (Lc) (R. et P.) Tiegh.

Effects of proanthocyanidin enriched extract from Ligaria cuneifolia on plasma cholesterol and hemorheological parameters. In vivo and In vitro studies.

Unlabelled: It was demonstrated that Ligaria cuneifolia (Lc) crude extract increased blood viscosity and decreased plasma cholesterol in rats. In the present study, we analyzed the Lc proanthocyanidin enriched fraction (PLc) to determine if it is capable of altering the hemorheological parameters while diminishing the plasma cholesterol. In vivo studies in adult male Wistar rats, randomized in three groups (n = 6 each one) were performed: 1.