Publications by authors named "Lecong Zhang"

Article Synopsis
  • - The study aimed to categorize psoriasis into three distinct subtypes (A-C) based on gene expression profiles from skin samples to improve personalized treatment options for patients.
  • - Subtype A showed high immune activation, subtype B had moderate activity, and subtype C was linked to tissue proliferation, each responding differently to various treatments like methotrexate and biologics.
  • - The findings highlight the importance of understanding the molecular differences among psoriasis subtypes to optimize treatment strategies for individuals, potentially leading to better outcomes.
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Triclosan (TCS) has been manufactured as an antibacterial compound for half a century. Currently, it is widely used in various personal care products; however, its potential adverse effects raise a lot of attention. Here, we create a long-term oral administration mouse model and identify the corresponding hepatotoxicity of TCS.

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Polystyrene microplastics (PS MPs) are micrometer-scale items degraded from plastics and have been detected in various organisms. PS MPs have been identified as causing cognitive, cardiac, intestinal, and hepatic damage. However, their role in liver regeneration under drug-induced liver injury remains unknown.

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