Next-Generation Vaccines: Nanovaccines in the Fight against SARS-CoV-2 Virus and beyond SARS-CoV-2.

The virus responsible for the coronavirus viral pandemic is the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Emerging SARS-CoV-2 variants caused by distinctive mutations within the viral spike glycoprotein of SARS-CoV-2 are considered the cause for the rapid spread of the disease and make it challenging to treat SARS-CoV-2. The manufacturing of appropriate efficient vaccines and therapeutics is the only option to combat this pandemic.

Protective Roles and Mechanism of Action of Plant Flavonoids against Hepatic Impairment: Recent Developments.

Background: The liver is one of the crucial organs in humans and is responsible for the regulation of diverse processes, including metabolism, secretion, and detoxification. Ingestion of alcohol and drugs, environmental pollutants, and irradiation are among the risk factors accountable for oxidative stress in the liver. Plant flavonoids have the potential to protect the liver from damage caused by a variety of chemicals.

Triazole-containing Heterocycles: Privileged Scaffolds in Anti- Drug Development.

Background: Chagas disease is a potentially life-threatening illness caused by the protozoan parasite Trypanosoma cruzi and is transmitted to humans through the excreta of infected blood-sucking triatomine bugs. According to the World Health Organization, 6 to 7 million people are infected with T. cruzi worldwide, mainly in Latin America, with more than 10000 deaths annually.

Influence of Magnetic Nanoparticles on Modified Polypyrrole/-Phenylediamine for Adsorption of Cr(VI) from Aqueous Solution.

A novel, modified polypyrrole/-phenylediamine (PPy-PD) composite, decorated with magnetite (FeO) nanoparticles, and prepared via an in-situ oxidative polymerisation, was investigated. The PPy-PD/FeO nanocomposite was employed for the removal of highly toxic oxyanion hexavalent chromium Cr(VI) from an aqueous solution. The structure and successful formation of the PPy-PD/FeO nanocomposite was confirmed and investigated using various techniques.