Bringing underserved communities life-saving aid through aerial logistics.

Autonomous drone delivery of medical supplies has improved access to health care for local communities in Africa.

Are child maltreatment and intimate partner violence associated with adult disordered eating?

Objective: Disordered eating is one of the most prevalent mental health concerns (Galmiche et al., 2019, Quick & Byrd-Bredbenner, 2013, Neumark-Sztainer et al., 2006).

Threats to Belonging, Immune Function, and Eating Behavior: an Examination of Sex and Gender Differences.

Purpose Of Review: The first goal of this review is to discuss the evidence linking belonging threats to immune function and food intake. The second goal is to evaluate whether the links among belonging threats, immune function, and eating behavior differ based on gender.

Recent Findings: Threats to belonging are linked to elevated herpesvirus antibody titers, dysregulated appetite-relevant hormones, and increased food consumption.

[PROPHYLAXIS OF COGNITIVE DEFICIENCY WHILE PERFORMING ЕNDARTERECTOMY IN PATIENTS, SUFFERING STENOTIC AFFECTIONS OF CAROTID ARTERIES: THE ROLE OF MULTIDISCIPLINARY APPROACH].

Efficacy of the cognitive deficiency prophylaxis was studied in patients, suffering stenotic affection of carotid arteries. Application of intraoperative neuroprotection, using neoton, have permitted to reduce the reperfusion syndrome signs rate from 35.6 to 3.

[THROMBOLYTIC THERAPY OF ACUTE VASCULAR DISEASES IN IRKUTSK REGION].

Cardiovascular diseases rank first as the cause of mortality, morbidity, and disability. This paper concerns evolution of thrombolytic therapy for acute coronary syndrome and ischemic stroke in the Irkutsk region characterized by low population density.

[Structural changes in membranes of proliferating leukocytes L-41 as affected by low doses of ionizing radiation].

The dose-dependent effects of gamma-radiation on the leucocyte cultures L-41 has been investigated. Irradiation by the dose of 0.25 Gy stimulates the cell proliferation while that by the doses of 1.

[Effect of 1,8-ANS on structural characteristics of cardiomyocytes sarcolemma].

The effect of sufan on structure properties of the rat cardiomyocyte sarcolemma was investigated. Fluorescence methods involving the probing with 1-anilino-8-naphthalene-sulfonate or pyrene and the self-fluorescence of membrane proteins was used. Effect of sufan on the cardiomyocyte sarcolemma structure has been determined to provoke the conformational disturbances.

[Structural rearrangement in leukocyte membranes under the effect of quercetin and linoleic acid hydroxamate].

The character of structural rearrangements in leukocyte membranes affected by 5-lipoxygenase inhibitors: quercetin and linoleic acid hydroxamate, has been investigated. Quercetin has been shown to induce the translocation of tryptophanyls and tyrosyls from membrane protein inner regions to their surface. Linoleic acid hydroxamate produces the analogous transition of tyrosine residues only.

Character of structural disturbances caused by chloroalkylamines in the model and erythrocyte membranes.

beta, beta-Dichlorodiethylamine is proved not to induce structural disturbances in phosphatidylcholine liposomes and erythrocyte membranes which is registered by fluorescence methods. Methyl-beta, beta-dichlorodiethylamine and metaxylyl-beta, beta-dichlorodiethylamine cause the increase in microviscosity of lipid bilayer hydrophobic areas in both erythrocyte membranes and liposomes. Besides, polarity of the latter also decreases, and the metaxylyl derivative alkylates nucleophilic centers of phospholipid phosphate groups in liposomes.

[Interaction of liposomes with erythrocytes in the process of their lysis].

Interaction of phosphatidyl choline liposomes with erythrocytes during spontaneous lysis of the latter has been studied. It is shown that hemoglobin which is released during the lysis of erythrocytes is found by liposomes which in their turn are absorbed on the external erythrocyte surface. In this case the binding of hemoglobin by liposomes takes place with a greater speed than its release during erythrocyte lysis and is accompanied by a change in its conformation.

[Structural effects in the sarcolemma of the cardiomyocytes under the action of modulators of the polyphosphoinositide system].

The influence of activators (Ca(2+)-channels stimulator BAY K 8644 and phospholipase C stimulator fMLP) and inhibitors (Ca(2+)-channels blocker verapamil and alpha 1-adrenoceptors blocker prazosin) of the polyphosphoinositide system on cardiomyocytes sarcolemma, was studied. The structural effects of the PPI modifiers seem to be one of the mechanisms of the PPI physiological activity at the membrane level.

[Structural effects in membranes after exposure to methyl (embiquin) and metaxylyl derivatives of chloroalkylamines].

Chloroaklylamine derivatives are studied for their effect on the structural organization of mitochondrion and microsome membranes of the cattle liver. The antitumoural preparation--embiquin is shown to increase microviscosity of hydrophobic zones of a lipid matrix of mitochondrial membranes and to decrease the quantity of immobilized cytochrome C, whereas it has no effect on microsomal membranes. It is established that the replacement of a methyl substituent in the nitrogen atom of chloroalkylamines by the metaxylyl one evokes no qualitative differences in the character of disturbances of the structural properties of mitochondrial membranes, however it induces structural perturbations in the microsomal membranes.

[Effect of the conditions of ultrasonic treatment on the characteristics of forming liposomes].

The conformity of the ultrasonic treatment influence on characteristics of the forming liposomes from phosphatidylcholine water dispersion has been studied by means of spectrophotometry, atomic absorption spectrometry, thin layer and gel chromatography and electron microscopy. Optimal treatment conditions which allow attaining relatively homogeneous suspension of small unilamellar vesicles with the low peroxidation level and minimal lysophospholipid contents have been determined.

[Complexing of bovine serum albumin with phosphatidyl choline liposomes].

Thermodynamic parameters of the bovine serum albumin interaction with phosphatidyl choline liposomes have been determined. It is shown that the bovine serum albumin is adsorbed on the liposomal surface without change of the globule conformation, the polar interactions making dominant contribution in immobilization. The complexing is characterized by a binding constant and a great number of binding sites.

[Properties of liposomes adsorbed by montmorillonite].

Adsorption of phosphatidylcholine liposomes by montmorillonite was studied for its effect on peroxidation of phospholipids and structure of the bilayer. The UV spectroscopy has shown that adsorption decreases peroxidation of lipids. A parameter is suggested for estimating an oxidation degree of lipids at the stage of the intensive formation of secondary products of their peroxidation.