Publications by authors named "Leanne Lucas"
Article Synopsis
- RH5 is a promising vaccine candidate against Plasmodium falciparum, showing some effectiveness in reducing parasite growth during human trials, especially when combined with Ripr and CyRPA.
- Researchers tested various combinations of these proteins in mice and rats to determine the best immune response and found that the DPX® adjuvant significantly enhanced the production of protective antibodies.
- While combining RH5 with other antigens showed potential, it may not provide better immunity than using RH5 alone, suggesting that future vaccines could explore different antigen combinations.
Collagen fibrils are the main constituent of the extracellular matrix surrounding eukaryotic cells. Although the assembly and structure of collagen fibrils is well characterized, very little appears to be known about one of the key determinants of their biological function-namely, the physico-chemical properties of their surface. One way to obtain surface-sensitive structural and chemical data is to take advantage of the near-field nature of surface- and tip-enhanced Raman spectroscopy.
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