Publications by authors named "Leanne Carijn Helgers"
Article Synopsis
- - ILC2s are important for type 2 immunity and play a role in chronic inflammatory conditions like asthma.
- - Research shows that resting ILC2s in humans retain a marker (CD45RO) associated with activated inflammatory ILC2s, while also decreasing another typical marker (CD127) in specific tissues.
- - When isolated and stimulated, these CD127-CD45RO+ ILC2s demonstrate enhanced growth and cytokine production, suggesting that human ILC2s can develop an innate immune memory, prompting a reevaluation of how these cells are identified.
